Hidden Mini-Proteins in the Dark Proteome May Hold Keys to Heart Disease
Scientists discovered hundreds of unknown mini-proteins in failing hearts, potentially reshaping how we understand disease at the cellular level.
Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,821 articles
Scientists discovered hundreds of unknown mini-proteins in failing hearts, potentially reshaping how we understand disease at the cellular level.
4-month senolytic treatment with D+Q cleared senescent RPE cells, reduced lipofuscin, and preserved vision in a preclinical dry AMD model.
A completed RCT from the University of Copenhagen tests whether aerobic exercise, time-restricted feeding, or NR supplementation best improves biological aging markers in healthy older adults.
A biomimetic nanoplatform combining cerium antioxidants, a natural flavonoid, and macrophage camouflage precisely targets injured kidneys to combat AKI.
New research reveals how peroxiredoxin proteins act as precision antioxidants and redox signaling hubs — with direct implications for cellular aging.
Salmon-derived PDRN prevents degradation of the longevity protein SIRT1 by reducing autophagy in UV- and oxidative stress-damaged skin cells.
A new review reveals how resveratrol suppresses neutrophil extracellular traps — immune structures tied to COVID-19, cancer, and organ injury.
Four anti-aging compounds — quercetin, fisetin, dasatinib, and sirolimus — all shifted gut microbiome composition toward healthier aging profiles.
RPL7A hijacks a circular RNA–protein complex to degrade SIRT6, accelerating lung adenocarcinoma progression and revealing a novel therapeutic target.
Go beyond the basics and explore the precise biochemical mechanisms by which hydrogen sulfide extends healthspan — from persulfidation to mitochondrial electron transport.
New imaging data shows one 25mg psilocybin dose alters brain anatomy, while sleep and APOE4 findings add to neurological health picture.
Niagen Bioscience launches a clinician-directed telehealth platform delivering at-home NAD+ subcutaneous injection kits to eligible US patients.