Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,821 articles
A new review proposes that the deteriorating extracellular matrix actively promotes senescent cell accumulation — a missing piece in aging biology.
Researcher behavior changes when observed — and this bias may be undermining the validity of longevity studies.
A 7,210-person PREDIMED cohort study finds each additional food species consumed reduces all-cause mortality risk by 9% in high-risk older adults.
A Delphi study of 62 cosmetic dermatologists identifies 23 evidence-backed topical ingredients for wrinkles, acne, dark spots, and more.
Scientists discover fibronectin forms a critical scaffold guiding stem cells during hair follicle regeneration, with implications for skin aging and repair.
A natural antioxidant carotenoid selectively binds TNFR2 in oocytes, blocking TNF-α signaling and dramatically improving embryo development outcomes.
A gut-derived compound called 4-HPA, produced when microbes metabolize resveratrol, reduces obesity and activates the longevity enzyme SIRT1.
Immunosenescence reshapes immune function in ways that fuel autoimmune disease — and new therapies targeting aging immune cells may reverse the damage.
A comprehensive 2025 review reveals how failing mitochondria fuel inflammation, metabolic chaos, and cellular senescence to accelerate aging.
A landmark review reveals obesity and aging share molecular hallmarks that accelerate cardiovascular disease, and how anti-obesity drugs may reverse this.
Asia's leading sarcopenia group expands diagnosis to middle age and introduces a broader muscle health framework tied to brain, bone, and immunity.
A new review maps how bioactive dietary compounds like fisetin, resveratrol, and ergothioneine extend healthy lifespan — using worms to fast-track human discoveries.
