Longevity & Aging
Cellular Senescence Drives GI Disease From Mouth to Pancreas
A landmark review maps how senescent cells fuel gastrointestinal diseases—and why clearing them could transform treatment.
Research Paper
May 4, 2026 0
Topic
Reversing Aging
Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,824 articles
Longevity & Aging
Premium
mTOR at the Molecular Frontier: Mechanisms, Therapeutics, and Longevity Engineering
A deep mechanistic exploration of mTOR complex architecture, allosteric regulation, and the cutting-edge therapeutic strategies targeting this pathway for healthspan extension.
TutorialAdvanced
May 4, 2026 0
Longevity & Aging
Loss of Y Chromosome Rewires Immune Cells and Triggers Abnormal X-Gene Activity in Aging Men
New single-cell RNA data reveals how Y chromosome loss reshapes immune cell behavior and unlocks cancer-linked X genes in older men.
Research Paper
May 4, 2026 0
Longevity & Aging
Night Shift Work Accelerates Aging and Reduces Life Expectancy by Nearly One Year
Large UK study reveals night shift workers age faster biologically and lose nearly a year of life expectancy.
Research Paper
May 3, 2026 0
Longevity & Aging
Long-Term Obesity Accelerates Biological Aging by 15% in Young Adults
Chilean study reveals obesity since childhood triggers molecular aging signatures including DNA changes and inflammation in 28-31 year olds.
Research Paper
May 3, 2026 0
Longevity & Aging
Aging and Atherosclerosis Create Vicious Cycle That Accelerates Both Diseases
New research reveals how aging promotes atherosclerosis while cardiovascular disease accelerates biological aging through shared molecular pathways.
Research Paper
May 3, 2026 0
Longevity & Aging
Anti-Inflammatory Drugs Show Promise for Slowing Kidney Disease and Heart Risk
New therapies targeting inflammation pathways could reduce cardiovascular disease and slow kidney disease progression in CKD patients.
Research Paper
May 3, 2026 0
Longevity & Aging
Five Drug Classes Show Promise for Extending Human Healthspan and Reversing Aging
Comprehensive review identifies senolytics, NAD+ precursors, mTOR inhibitors and other compounds targeting aging hallmarks.
Research Paper
May 3, 2026 0
Longevity & Aging
DNA Repair Enzymes Control T Cell Function and Immune Aging
TET and TDG proteins regulate DNA methylation in T cells, affecting immune responses, inflammation, and age-related diseases.
Research Paper
May 3, 2026 0
Longevity & Aging
Premium
mTOR's Control Room: Nutrient Sensors, Signaling Cascades, and Aging
Go beyond the basics and explore how mTOR actually reads nutrient signals, which molecular players are involved, and why the balance between mTOR complexes determines whether you age faster or slower.
TutorialIntermediate
May 3, 2026 0
Longevity & Aging
FDA Real-Time Clinical Trials Could Speed Up Drug Approvals for Longevity Therapies
The FDA is piloting live data-streaming in clinical trials, promising faster drug approvals but raising concerns about data quality and bias.
Press Release
May 3, 2026 0
Longevity & Aging
Cold Exposure Reshapes Human Blood Proteins Toward Heart Protection and Slower Aging
A first-of-its-kind proteomics study finds acute cold exposure shifts 185 circulating proteins in a cardioprotective, anti-aging direction across independent cohorts.
Research Paper
May 3, 2026 0