Supplements, peptides, nootropics, and bioactive compounds for health optimization
130 articles
Expert reviews compare leading NMN and NR supplements on clinical evidence, purity, and value — with key caveats on what the science can and cannot yet prove.
A rigorous product review reveals major quality gaps in NAD+ supplements and what dosing evidence actually supports.
A head-to-head comparison of NMN and NR supplements reveals distinct benefit profiles — and major quality gaps across popular brands.
A quercetin, NR, urolithin A, and alpha-lipoic acid combination boosted remaining lifespan in aged mice by 33%, even on a Western diet.
Two popular longevity drugs show evidence of interfering with the body's response to exercise — a critical tradeoff for active users.
The FDA will convene advisory panels in July 2025 to reconsider whether compounding pharmacies can legally produce certain popular peptides removed from approved lists in 2023.
Longevity expert Bryan Johnson shares critical safety considerations and potential risks you need to know before using peptides.
New study reveals popular bodybuilding supplement ligandrol impairs cardiovascular fitness and hormonal health despite muscle strength gains.
New rat study shows zinc methionine at 75mg/kg reduces insulin resistance and mTOR gene expression in polycystic ovarian syndrome.
Research challenges popular belief that NAD supplements improve muscle performance, finding minimal functional impact when NAD levels drop.
Meta-analysis of 69 studies reveals creatine's differential effects on upper/lower body strength across populations.
Three-month study shows PQQ increases mitochondrial biogenesis and antioxidant capacity but has no impact on body weight or energy expenditure.
