Supplements, peptides, nootropics, and bioactive compounds for health optimization
155 articles
New research finds that serum FT3 may reveal inadequate thyroid hormone action even when TSH appears normal in post-thyroidectomy patients.
Single-nucleus RNA sequencing reveals TRT partially reverses fibrotic and inflammatory muscle changes in hypogonadal Klinefelter men.
A JAMA viewpoint exposes how illicit injectable peptides are escaping regulation as the line between medicine and enhancement blurs.
GLP-1 receptor agonists used for weight loss may also restore male reproductive hormones and improve sperm parameters.
A Phase II crossover trial directly compares Chronocort and Plenadren to find the optimal hydrocortisone replacement for adrenal insufficiency.
NIEHS researchers investigated how low or absent GnRH affects puberty, reproductive hormones, and fertility in adolescents and adults.
Dr. Abud Bakri covers BPC-157, epithalon, GHK-Cu, GLP-1s, and growth hormone peptides — separating real evidence from hype.
Both NMN and NR raise NAD+ levels in humans, but clinical proof of anti-aging benefits is still lacking — and product quality varies widely.
A Mendelian randomization study finds genetically elevated DHEA-S is associated with shorter lifespan in men—raising questions about unregulated DHEA supplementation.
Attia lays out a rigorous, personalized decision framework for evaluating medications and supplements — cutting through hype with evidence hierarchy and risk math.
A candid breakdown of top NAD+ booster brands reveals strong biomarker data but slim evidence for real longevity outcomes.
A double-blind RCT finds daily spermidine supplementation reverses immune senescence markers and boosts vaccine antibody responses in adults over 65.
