Heart Health
Senolytics, Gene Therapy and Lifestyle Can Slow Cardiovascular Aging
A 2025 review maps the molecular drivers of cardiac aging and evaluates drugs, CRISPR, stem cells, and lifestyle as countermeasures.
Research Paper
May 11, 2026 0
Results for "Dasatinib Quercetin"
20 articles
Longevity & Aging
Inside the Lab Methods Scientists Use to Test Senolytic Drugs
A comprehensive review of in vitro assays for inducing cellular senescence and screening senolytic drugs, highlighting key challenges in clinical translation.
Research Paper
May 10, 2026 0
Longevity & Aging
Three Different Drugs Each Reverse Oxygen-Induced Lung Aging in Premature Infant Cells
Fucoidan, dasatinib+quercetin, and MitoQ each counteract hyperoxia-driven cellular senescence in fetal airway cells via distinct mechanisms.
Research Paper
May 10, 2026 0
Longevity & Aging
Chemotherapy Destroys Bones by Triggering Senescence in Marrow Fat Cells
A new study pinpoints chemotherapy-induced senescent bone marrow cells as the culprit behind bone loss, and shows senolytics can prevent it.
Research Paper
May 9, 2026 0
Longevity & Aging
First Senolytic Trial in Alzheimer's Patients Reveals Promising Biomarker Shifts
A phase 1 trial of dasatinib + quercetin in 5 early AD patients uncovers fluid biomarker changes that could guide future senolytic trials.
Research Paper
May 7, 2026 0
Longevity & Aging
Dasatinib and Quercetin Reverse Retinal Aging in Dry AMD Mouse Model
4-month senolytic treatment with D+Q cleared senescent RPE cells, reduced lipofuscin, and preserved vision in a preclinical dry AMD model.
Research Paper
May 7, 2026 0
Cancer Research
Senolytics Fail to Protect Bone From Chemotherapy-Induced Loss
A mouse study finds that senolytic drugs cannot prevent chemotherapy-driven bone loss, challenging a leading hypothesis about its cause.
Research Paper
May 7, 2026 0
Regenerative Medicine
Senolytic Drug Combo Dasatinib and Quercetin Accelerates Rotator Cuff Healing in Aged Rats
A senolytic pairing of dasatinib and quercetin cleared senescent cells at the tendon-bone junction, dramatically improving repair strength in aged rats.
Research Paper
May 7, 2026 0
Autoimmune & Arthritis
Senolytics and Epalrestat Show Promise for Slowing Polycystic Kidney Disease
Senescent cells drive cyst growth in ADPKD, and targeting them with senolytics or the aldose reductase inhibitor epalrestat delays disease progression.
Research Paper
May 6, 2026 0
Regenerative Medicine
Smart Hydrogel Plus Senolytics and Exosomes Reverses Disc Degeneration in Animal Models
A novel anti-swelling hydrogel loaded with dasatinib, quercetin, and nucleus pulposus exosomes clears senescent cells and restores disc integrity in rats and goats.
Research Paper
May 6, 2026 0
Longevity & Aging
Senolytic Drug Combo Slows Age-Related Hearing Loss in Mice
Dasatinib and quercetin clear senescent cochlear cells, reducing inflammation and preserving hair cells in aging mice.
Research Paper
May 6, 2026 0
Longevity & Aging
Five Drug Classes Show Promise for Extending Human Healthspan and Reversing Aging
Comprehensive review identifies senolytics, NAD+ precursors, mTOR inhibitors and other compounds targeting aging hallmarks.
Research Paper
May 3, 2026 0
Regenerative Medicine
Premium
Rewriting the Code: Advanced Stem Cell Rejuvenation Strategies
Dive deep into partial reprogramming, niche remodeling, senolytics, and cutting-edge clinical therapies — the molecular toolkit for reversing stem cell aging.
TutorialAdvanced
May 2, 2026 0
Autoimmune & Arthritis
Premium
Reprogramming the Aged Immune System: Senolytics, Cytokine Blockade, and Epigenetic Rejuvenation
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
TutorialAdvanced
May 2, 2026 0
Heart Health
Premium
Vascular Rejuvenation: Advanced Interventions to Reverse Arterial Aging
Dive deep into the molecular mechanisms of vascular aging and explore cutting-edge interventions — from senolytic therapies and nitric oxide restoration to exercise-induced remodeling and emerging pharmacological approaches — that are redefining what's possible in cardiovascular longevity.
TutorialAdvanced
May 2, 2026 0
Regenerative Medicine
Premium
ECM Remodeling: Therapeutic Frontiers and Precision Interventions
Master the cutting-edge molecular targets, clinical trial data, and emerging therapeutic strategies aimed at reversing ECM aging — from senolytic combinations to biomaterial scaffolds and epigenetic reprogramming.
TutorialAdvanced
May 1, 2026 0
Longevity & Aging
Popular Senolytic Drug Combo Damages Brain Myelin in Mice
Dasatinib and quercetin, a leading senolytic combo, unexpectedly reduced myelination in healthy mouse brains, mimicking multiple sclerosis damage.
Press Release
Apr 29, 2026 0
Longevity & Aging
Senolytic Drug Combo Reverses Age-Related Bone Loss in Mice
Dasatinib plus quercetin cleared senescent cells and reduced inflammation, improving alveolar bone health in aged mice.
Research Paper
Apr 25, 2026 0
Regenerative Medicine
Premium
p16/p21-SASP Pathways: Molecular Targets for Senolytic Drug Development
Explore the molecular mechanisms of cellular senescence and how p16/p21 pathways drive SASP production, plus cutting-edge senolytic drug targets.
TutorialAdvanced
Apr 14, 2026 0
Longevity & Aging
Cancer Drugs Repurposed as Senolytic Therapies Show Promise for Aging
Review reveals how anti-cancer drugs are being repurposed to eliminate senescent cells, opening new pathways for longevity treatments.
Research Paper
Apr 10, 2026 0
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