New Research Tool MetaboMiNR Advances Nuclear Receptor and Metabolism Studies
Scientists develop innovative computational tool to better understand how nuclear receptors control metabolism and aging processes.
20 articles
Scientists develop innovative computational tool to better understand how nuclear receptors control metabolism and aging processes.
Advanced computational methods integrate genomics, metabolomics, and AI to accelerate discovery of bioactive compounds from natural sources.
Pituitary adenoma receptor profiles and granulation patterns determine which somatostatin drugs work best for acromegaly patients.
An 8-week feasibility trial combines NMN, urolithin A, creatine, and exercise to target individual aging patterns.
A mechanistic deep dive into hormone replacement therapy evidence, growth hormone secretagogues, DHEA pharmacology, and cutting-edge endocrine reprogramming strategies — with clinical trial data and actionable protocols.
A C. elegans study finds V14™ outperforms AG1® in preserving movement with age, with transcriptomics revealing metabolic and stress-response pathway shifts.
A biomarker-guided treatment strategy outperforms traditional stepwise therapy, achieving hormonal control in nearly 80% of acromegaly patients.
Disease names shape how doctors diagnose, researchers study, and patients understand their conditions — PCOS is a case study in getting it wrong.
Small trial tests hormone-based therapy to combat age-related muscle and bone loss in vulnerable adults.
A candid breakdown of top NAD+ booster brands reveals strong biomarker data but slim evidence for real longevity outcomes.
New study reveals reduced forms of NAD precursors trigger broader cellular changes and more potent longevity benefits than current supplements.
New testing framework helps doctors quickly identify harmful mutations in PPARγ gene linked to rare fat disorders and cancer.
Expert reviews compare leading senolytic and NAD+ supplement brands on ingredients, evidence quality, and value.
Research reveals how the thyroid hormone metabolite Triac enhances bone mineralization and calcium uptake at nanomolar concentrations.
Scientists discover how cholecystokinin receptors regulate digestion, fat storage, and fertility, revealing new metabolic pathways.
A completed Mayo Clinic trial examined whether nicotinamide riboside can preserve bone density, muscle mass, and metabolic function in healthy older adults.
Go beyond the basics and explore the molecular machinery behind GH and IGF-1 signaling — from receptor activation to downstream effects on metabolism, muscle, and lifespan.
Scientists develop clinical decision tool to overcome cancer's adaptive resistance mechanisms through redox pathway targeting.
A molecule from aged garlic activates a key longevity pathway in fat tissue, signaling the brain to restore muscle strength in old mice.
A completed Nestlé-sponsored trial directly compared three popular NAD precursors head-to-head in healthy adults.