Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1290 articles
Scientists pinpoint the AKG-IDH1-RPS23 axis as a key regulator of stem cell senescence, opening new doors for anti-aging metabolic therapies.
Senescent tumor endothelial cells secrete INHBB under diabetic conditions, accelerating pancreatic cancer—and blocking its receptor shows therapeutic promise.
Restoring regulatory T cells prevents gut leakiness, dysbiosis, and systemic inflammation—extending healthspan in a mouse aging model.
Discover what free radicals and reactive oxygen species actually are, why they're not purely villains, and how your body uses them as clever signals — with practical steps to keep the balance right for healthy aging.
A major meta-analysis reveals widespread underdiagnosis of Lewy body dementia, the second most common degenerative dementia after Alzheimer's.
A 43-year study of 131,000+ adults found moderate caffeine intake cuts dementia risk by 35% — but more isn't better.
COYA 302 combines low-dose IL-2 and CTLA-4 Ig to boost regulatory T cells and curb ALS-driving inflammation, now on an expedited FDA path.
WHOOP is adding in-app telehealth this summer, letting clinicians analyze your continuous biometric data alongside medical records and lab work.
A comprehensive review maps every major in vitro aging model—from Hayflick's fibroblasts to iPSCs—and the interventions that reverse cellular aging.
The International Society of Sports Nutrition's comprehensive 2025 review affirms HMB's safety and multi-faceted benefits for muscle, performance, and aging.
Ergothioneine, found in edible fungi, activates SIRT1/Nrf2 signaling in hair follicle cells to reduce oxidative damage and reverse aging-related hair loss.
A Mendelian randomization study identifies GPX1 as a shared druggable target for frailty and hypertension, mediated by glycine and carnitine pathways.
