How the Brain Cleans Itself During Sleep and Why It Matters for Aging
A landmark review unifies brain waste clearance and immune surveillance, revealing how CSF flow, sleep, and meningeal immunity protect against neurodegeneration.
Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1290 articles
A landmark review unifies brain waste clearance and immune surveillance, revealing how CSF flow, sleep, and meningeal immunity protect against neurodegeneration.
Intermittent fisetin dosing in old mice reduced frailty and boosted grip strength, matching results from genetic and synthetic senolytic approaches.
Procyanidin C1, a natural polyphenol, reduces aging-related skin scarring by targeting EGFR and shutting down fibrosis signaling pathways.
A comprehensive review reveals how one gut bacterium influences metabolism, immunity, cancer response, and longevity across multiple disease states.
A 2025 narrative review maps how regenerative medicine, epigenetics, AI, and microbiome science are transforming cosmetic dermatology.
A landmark 2025 review maps how gut bacteria shift across your lifespan and reveals therapies that could slow biological aging.
Vasa Therapeutics advances VS-214, a peptide targeting poor limb circulation, toward first human trials in 2026 — addressing a massively underserved condition.
A new webinar tackles the real question in NAD+ supplementation: whether pills, injections, or pens produce meaningfully different health outcomes.
Recent NIH-funded studies map pancreatic cells, improve heart risk prediction, and reveal testosterone's role in brain tumors.
New cohort data revises assumptions about US life expectancy gaps, showing near-universal gains for those born 1941–2000.
A newly characterized inner mitochondrial protein reshapes cristae structure, enhances energy output, and extends lifespan in transgenic flies.
A new study reveals how collapsing mitochondrial structure in kidney cells fuels oxidative stress and age-related kidney decline.