How Sugar-Coated Proteins Drive Aging and Diabetes at the Molecular Level
A new review reveals how protein glycosylation—a key cellular modification—fuels aging and diabetes, and how phytochemicals may intervene.
Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,811 articles
A new review reveals how protein glycosylation—a key cellular modification—fuels aging and diabetes, and how phytochemicals may intervene.
A sweeping review maps how telomerase inhibitors evolved from lab concept to approved drug, spotlighting imetelstat's landmark approval in blood cancers.
Scientists identify TRIM24 as a master regulator of ALT telomere maintenance, revealing a new epigenetic pathway cancer cells use to avoid aging.
Scientists uncover how two major mitophagy pathways are coordinated via ubiquitylation and mitochondrial import stress, with big implications for aging.
A comprehensive 2026 review reveals how mitochondrial self-cleaning gone wrong underlies neurodegeneration, heart disease, cancer, and aging.
A hypothesis paper proposes that near-infrared light activates mitochondrial melatonin synthesis, potentially shielding aging neurons from oxidative damage.
Compounds like metformin, rapamycin, and resveratrol may replicate longevity benefits of calorie restriction—without actually eating less.
A 374-patient multiomics study maps AML's proteomic landscape, uncovers hematopoietic aging patterns, and builds a prognostic scoring tool.
A large study finds low-risk pancreatic cysts carry a dramatically elevated cancer risk, with over a quarter of cases emerging after 5 years.
China introduces a structured national curriculum training doctors in healthspan, aging biology, AI diagnostics, and preventive care.
New research reveals primary and secondary senescent cells behave differently, opening targeted paths to slow aging at the cellular level.
Lysoway's LW-1017 aims to restore lysosomal function in aging brains, potentially slowing Alzheimer's before toxic proteins accumulate.