Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1290 articles
A 2025 meta-analysis of 35 RCTs (~25,000 adults 50+) quantifies how diet, exercise, sleep, and social ties each reduce aging-related decline.
University of Pittsburgh researchers weigh the science of fasting, concluding benefits are plausible but unproven—and call for rigorous human trials.
A rigorous 2025 review dissects fasting biology, cardiometabolic benefits, and underappreciated bone health risks from intermittent fasting.
A 2025 study shows epitalon lengthens telomeres in normal cells via telomerase and in cancer cells via ALT, offering new anti-aging insights.
Scientists mapped 5,416 circulating proteins across 59 diseases, revealing shared and unique protein signatures that could transform precision medicine.
A mechanistic deep-dive into the molecular architecture of redox signaling — from cysteine oxidation chemistry to therapeutic targeting of NRF2, NADPH oxidases, and mitochondrial ROS in the context of aging.
Diranersen reduced tau biomarkers and slowed cognitive decline in early Alzheimer's patients, marking a milestone for tau-directed therapy.
NeuroVision acquires Durin Life Sciences to combine blood biomarkers and retinal imaging for earlier Alzheimer's and Parkinson's detection.
As DEXA body composition testing booms in longevity circles, a new quality standard aims to separate trustworthy data from cheap, unreliable scans.
Buck Institute finds APOE2 boosts DNA repair and blocks cellular senescence in neurons, reframing Alzheimer's protection.
Dr Poonam Desai argues that personalized medicine rings hollow while clinical frameworks still use male biology as the default standard.
A 452-person study maps how inflammaging biomarkers diverge by sex across age groups, revealing the biological roots of the sex-frailty paradox.
