420 articles in this topic
A 10-gene-edited pig liver was transplanted into a living human for the first time, functioning for 31 days before removal due to a novel complication.
Two patients survived 40–60 days with genetically modified pig hearts. A new Circulation review maps the road ahead.
PBAE nanoparticles deliver two genes directly into scar tissue, converting astroglia into functional neurons and dissolving the scar barrier.
A mitochondrial sirtuin may hold the key to treating degenerative disc disease and the chronic low back pain it causes.
A novel injectable platform combining miR-197-3p and Prussian blue nanozymes reverses chondrocyte senescence and restores cartilage in OA models.
Arvinas' vepdegestrant becomes the first PROTAC to clear Phase 3 trials, targeting disease proteins for destruction rather than just blocking them.
Scientists engineer mammary organoids that secrete anticancer drugs while simultaneously regenerating functional breast tissue after surgery.
Japan's April 2026 revised guidelines now govern stem cell-based embryo models, marking a global regulatory milestone.
A biodegradable microneedle stent achieves sutureless intestinal anastomosis while releasing anti-inflammatory drugs triggered by local inflammation.
A precision CAR T cell therapy wipes out disease-driving myelofibrosis stem cells while sparing healthy ones — a potential cure candidate.
Researchers silenced nearly every expressed gene in human iPSCs, creating a landmark map of pluripotency's genetic architecture.
A new prime editing approach gives scientists precise genetic control over filamentous fungi, opening the door to novel bioactive compounds.
