Cancer

675 articles in this topic

Engineered Bacteria Could Become Precision Weapons Against Tumors
Cancer Research

Engineered Bacteria Could Become Precision Weapons Against Tumors

A new perspective in Nature Cancer outlines how genetically engineered bacteria can target and destroy tumors from within.

Review
Jun 5, 2026 0
Sputum and Microbiome Signatures May Predict Immunotherapy Response in Lung Cancer
Cancer Research

Sputum and Microbiome Signatures May Predict Immunotherapy Response in Lung Cancer

A completed French trial explores how gut and airway microbiota, blood, and sputum biomarkers relate to immunotherapy outcomes in metastatic NSCLC.

Clinical Trial
Jun 4, 2026 0
Triple Drug Combo Targets Richter's Syndrome in Completed Phase 2 Trial
Cancer Research

Triple Drug Combo Targets Richter's Syndrome in Completed Phase 2 Trial

A phase 2 trial tests obinutuzumab, ibrutinib, and venetoclax in Richter's syndrome, a deadly CLL transformation with few treatment options.

Clinical Trial
Jun 4, 2026 0
Tumor Cell State Predicts Who Responds to Immunotherapy in Glioblastoma
Cancer Research

Tumor Cell State Predicts Who Responds to Immunotherapy in Glioblastoma

A large genomic study finds mesenchymal glioblastoma responds better to immune checkpoint blockade, opening a path to smarter patient selection.

Research Paper
Jun 4, 2026 0
Itaconate Starves Lung Tumors by Blocking a Key Metabolic Enzyme
Cancer Research

Itaconate Starves Lung Tumors by Blocking a Key Metabolic Enzyme

A macrophage-derived metabolite rewires tumor metabolism and flips immune cells from tumor-promoting to tumor-fighting.

Research Paper
Jun 4, 2026 0
Single Protein Knockout Keeps Cancer-Fighting CAR T Cells Alive Longer
Cancer Research

Single Protein Knockout Keeps Cancer-Fighting CAR T Cells Alive Longer

Disabling the NFIL3 protein prevents CAR T cell exhaustion, boosting tumor-fighting power in animal models of hard-to-treat cancers.

Press Release
Jun 3, 2026 0
Blocking PINK1 Triggers Explosive Cancer Cell Death in Neuroblastoma
Cancer Research

Blocking PINK1 Triggers Explosive Cancer Cell Death in Neuroblastoma

Inhibiting the mitophagy kinase PINK1 amplifies mitochondrial ROS, activating a BAX-caspase-GSDME cascade that destroys neuroblastoma cells via pyroptosis.

Research Paper
Jun 3, 2026 0
ALT Cancer Cells Share Telomere End Structure With Normal Cells Despite Rogue Lengthening
Cancer Research

ALT Cancer Cells Share Telomere End Structure With Normal Cells Despite Rogue Lengthening

END-seq reveals ALT-positive cancer telomeres share canonical 5′ ATC termini with normal cells, but harbor uniquely abundant single-stranded DNA regions.

Research Paper
Jun 3, 2026 0
Telomere Shortening Mapped Across 1,800 Blood Cancer Patients Reveals Genetic Patterns
Cancer Research

Telomere Shortening Mapped Across 1,800 Blood Cancer Patients Reveals Genetic Patterns

A landmark WGS study of 1,804 myeloid neoplasia patients uncovers how telomere length varies by mutation type and cancer subtype.

Research Paper
Jun 3, 2026 0
Senescent Tumor Cells Expressing PD-L2 Blunt Chemotherapy Effectiveness
Cancer Research

Senescent Tumor Cells Expressing PD-L2 Blunt Chemotherapy Effectiveness

Intratumoral senescent cells shielded by PD-L2 may explain why chemotherapy often falls short — and point to a new combination strategy.

Research Paper
Jun 3, 2026 0
How a Common Oral Bacterium Quietly Drives Cancer Growth
Cancer Research

How a Common Oral Bacterium Quietly Drives Cancer Growth

Fusobacterium nucleatum has shifted from suspected bystander to confirmed cancer driver — here's what the science reveals.

Review
Jun 3, 2026 0
Cancer Research Exposes Mitochondria as Dynamic Shape-Shifting Powerhouses
Cancer Research

Cancer Research Exposes Mitochondria as Dynamic Shape-Shifting Powerhouses

New review reveals how cancer biology has fundamentally transformed our understanding of mitochondrial plasticity and its implications beyond oncology.

Research Paper
Jun 3, 2026 0
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