Bacterial Immunotherapy Enters Human Trials for Deadliest Pancreatic Cancer
Matter Bio files first IND for Listeria-based therapy targeting pancreatic cancer, merging oncology and longevity science.
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Matter Bio files first IND for Listeria-based therapy targeting pancreatic cancer, merging oncology and longevity science.
Researchers built a machine learning imaging pipeline to detect cerebral microhemorrhages and tested SS-31 (elamipretide) in aged hypertensive mice.
A comprehensive GeneReviews update on Barth syndrome outlines diagnosis, new targeted therapy, and surveillance strategies for this rare X-linked disorder.
A comprehensive review of pathophysiology, genetics, and emerging therapies for mitochondrial myopathies, spotlighting elamipretide and gene therapy.
The first disease-specific treatment for Barth syndrome gains FDA accelerated approval, targeting mitochondrial dysfunction to restore muscle strength.
Deleting GTPBP3 in endothelial cells blocks angiogenesis via mtROS overload β and a mitochondria-targeted antioxidant reverses the damage.
A comprehensive review in CA Cancer J Clin maps the molecular biology, treatment strategies, and equity gaps in high-grade serous ovarian cancer.
A 2-year clinical trial testing Juice Plus+ products against low-grade inflammation and biological aging markers in overweight seniors was terminated before completion.
Mendelian randomization links circulating inflammatory proteins to retinal microvascular changes, heart disease risk, and lifespan β establishing causal direction.
A phase 2b trial finds allogeneic MSC infusions improved 6-minute walk distance by 63 meters vs placebo at 9 months in frail older adults.
A 2025 review maps the molecular mechanisms driving cardiovascular agingβfrom inflammaging to ECM remodelingβand outlines emerging therapies.
A Phase 2 trial testing rituximab, infliximab, and tocilizumab for hard-to-treat non-ANCA vasculitis was terminated before completion.