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Bacterial Immunotherapy Enters Human Trials for Deadliest Pancreatic Cancer
Longevity & Aging

Bacterial Immunotherapy Enters Human Trials for Deadliest Pancreatic Cancer

Matter Bio files first IND for Listeria-based therapy targeting pancreatic cancer, merging oncology and longevity science.

Press Release
May 20, 2026 0
ML Pipeline Advances Detection of Age-Related Brain Microbleeds in Mouse Model
Brain Health

ML Pipeline Advances Detection of Age-Related Brain Microbleeds in Mouse Model

Researchers built a machine learning imaging pipeline to detect cerebral microhemorrhages and tested SS-31 (elamipretide) in aged hypertensive mice.

Research Paper
May 20, 2026 0
Barth Syndrome Management Gets a Boost With Targeted Elamipretide Therapy
Heart Health

Barth Syndrome Management Gets a Boost With Targeted Elamipretide Therapy

A comprehensive GeneReviews update on Barth syndrome outlines diagnosis, new targeted therapy, and surveillance strategies for this rare X-linked disorder.

Research Paper
May 20, 2026 0
Mitochondrial Myopathies in 2025: What Treatments Actually Work
Regenerative Medicine

Mitochondrial Myopathies in 2025: What Treatments Actually Work

A comprehensive review of pathophysiology, genetics, and emerging therapies for mitochondrial myopathies, spotlighting elamipretide and gene therapy.

Research Paper
May 20, 2026 0
Elamipretide Wins First FDA Approval for Barth Syndrome Via Mitochondrial Repair
Heart Health

Elamipretide Wins First FDA Approval for Barth Syndrome Via Mitochondrial Repair

The first disease-specific treatment for Barth syndrome gains FDA accelerated approval, targeting mitochondrial dysfunction to restore muscle strength.

Research Paper
May 20, 2026 0
Mitochondrial Protein GTPBP3 Found Essential for Blood Vessel Growth and Ischemia Recovery
Heart Health

Mitochondrial Protein GTPBP3 Found Essential for Blood Vessel Growth and Ischemia Recovery

Deleting GTPBP3 in endothelial cells blocks angiogenesis via mtROS overload β€” and a mitochondria-targeted antioxidant reverses the damage.

Research Paper
May 20, 2026 0
Personalized Medicine Is Reshaping How We Treat the Deadliest Ovarian Cancer
Cancer Research

Personalized Medicine Is Reshaping How We Treat the Deadliest Ovarian Cancer

A comprehensive review in CA Cancer J Clin maps the molecular biology, treatment strategies, and equity gaps in high-grade serous ovarian cancer.

Research Paper
May 20, 2026 0
Two-Year Plant-Based Supplement Trial for Inflammaging in Overweight Seniors Terminated Early
Heart Health

Two-Year Plant-Based Supplement Trial for Inflammaging in Overweight Seniors Terminated Early

A 2-year clinical trial testing Juice Plus+ products against low-grade inflammation and biological aging markers in overweight seniors was terminated before completion.

Clinical Trial
May 20, 2026 0
Inflammaging Biomarkers Causally Reshape Retinal Vessels and Predict Cardiovascular Fate
Heart Health

Inflammaging Biomarkers Causally Reshape Retinal Vessels and Predict Cardiovascular Fate

Mendelian randomization links circulating inflammatory proteins to retinal microvascular changes, heart disease risk, and lifespan β€” establishing causal direction.

Research Paper
May 20, 2026 0
Stem Cell Therapy Laromestrocel Boosts Walking Ability in Frail Older Adults
Regenerative Medicine

Stem Cell Therapy Laromestrocel Boosts Walking Ability in Frail Older Adults

A phase 2b trial finds allogeneic MSC infusions improved 6-minute walk distance by 63 meters vs placebo at 9 months in frail older adults.

Research Paper
May 20, 2026 0
How Your Heart Ages and What Science Can Do to Slow It Down
Heart Health

How Your Heart Ages and What Science Can Do to Slow It Down

A 2025 review maps the molecular mechanisms driving cardiovascular agingβ€”from inflammaging to ECM remodelingβ€”and outlines emerging therapies.

Research Paper
May 20, 2026 0
UK Trial of Biologics for Refractory Rare Vasculitis Terminated Early
Autoimmune & Arthritis

UK Trial of Biologics for Refractory Rare Vasculitis Terminated Early

A Phase 2 trial testing rituximab, infliximab, and tocilizumab for hard-to-treat non-ANCA vasculitis was terminated before completion.

Clinical Trial
May 20, 2026 0
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