Advanced Therapies

4,573 articles in this topic

Bivalent Chromatin Marks Decoded as Master Switches for Blood Cell Formation
Longevity & Aging

Bivalent Chromatin Marks Decoded as Master Switches for Blood Cell Formation

A landmark study reveals how competing histone modifications act as a molecular toggle governing blood stem cell differentiation and tissue homeostasis.

Research Paper
Jul 2, 2026 0
FDA Clears CRISPR Gene Therapy Casgevy for Children as Young as Age 2 with Sickle Cell
Longevity & Aging

FDA Clears CRISPR Gene Therapy Casgevy for Children as Young as Age 2 with Sickle Cell

The FDA expanded approval of Casgevy, a CRISPR-based gene therapy, to children aged 2+ with sickle cell disease, offering a potential cure.

Press Release
Jul 2, 2026 0
Genomic Test May Spare More Early Breast Cancer Patients From Chemotherapy
Longevity & Aging

Genomic Test May Spare More Early Breast Cancer Patients From Chemotherapy

The OPTIMA trial shows genomic testing could safely help more women with early breast cancer skip chemo, including premenopausal women.

Press Release
Jul 2, 2026 0
Older Adults With Obesity Now Match Normal-BMI Peers on Key Heart Risk Markers
Longevity & Aging

Older Adults With Obesity Now Match Normal-BMI Peers on Key Heart Risk Markers

A major global study finds BMI-linked gaps in blood pressure and cholesterol have nearly vanished for older adults — but young adults remain at elevated risk.

Press Release
Jul 2, 2026 0
FDA Approves Orca Bio T Cell Therapy That Cuts Graft-Versus-Host Disease Risk
Longevity & Aging

FDA Approves Orca Bio T Cell Therapy That Cuts Graft-Versus-Host Disease Risk

Tregzi, a personalized T cell therapy, wins FDA approval to reduce dangerous immune complications in blood cancer stem cell transplant patients.

Press Release
Jul 2, 2026 0
Statins and Blood Pressure Drugs Are Quietly Reshaping Obesity's Cardiovascular Risks
Longevity & Aging

Statins and Blood Pressure Drugs Are Quietly Reshaping Obesity's Cardiovascular Risks

A 25-year Lancet study finds adults over 40 with obesity now show cardiovascular markers rivaling normal-weight peers, thanks to medications.

Press Release
Jul 2, 2026 0
June 2026 Longevity Breakthroughs Span Gene Therapy to Gut-Lung Axis
Longevity & Aging

June 2026 Longevity Breakthroughs Span Gene Therapy to Gut-Lung Axis

From a 20% lifespan boost in mice to Alzheimer's glycosylation hallmarks, June's research roundup delivers dense longevity science.

Press Release
Jul 2, 2026 0
How PARN and Telomerase Cooperate to Control Aging and Cancer Risk
Longevity & Aging

How PARN and Telomerase Cooperate to Control Aging and Cancer Risk

A new review reveals how the deadenylase PARN governs telomerase RNA maturation, linking RNA decay to telomere length, aging, and disease.

Research Paper
Jul 2, 2026 0
Inherited Bone Marrow Failure Syndromes Explained from Root Causes to Clinical Signs
Regenerative Medicine

Inherited Bone Marrow Failure Syndromes Explained from Root Causes to Clinical Signs

A comprehensive review of inherited bone marrow failure, covering genetic causes, major syndromes, and the cytopenias that define them.

Research Paper
Jul 2, 2026 0
AI-Designed Gene Therapy Extends Lifespan 83% in Progeria Mouse Models
Longevity & Aging

AI-Designed Gene Therapy Extends Lifespan 83% in Progeria Mouse Models

An AI-engineered antisense oligonucleotide slashes toxic progerin levels, reverses cardiovascular damage, and dramatically extends lifespan in progeria models.

Research Paper
Jul 2, 2026 0
Senolytic Drug Combo Rejuvenates Aged Kidneys at the Systems Level
Regenerative Medicine

Senolytic Drug Combo Rejuvenates Aged Kidneys at the Systems Level

Dasatinib + quercetin clears senescent kidney cells, restores anti-aging protein Klotho, and reverses transcriptional aging across multiple renal cell types.

Research Paper
Jul 2, 2026 0
Muscle Loss and Bone Loss Are Bidirectional Threats With Shared Biological Roots
Longevity & Aging

Muscle Loss and Bone Loss Are Bidirectional Threats With Shared Biological Roots

A large multi-omics study confirms sarcopenia and osteoporosis fuel each other — and share genetic, protein, and metabolic pathways.

Research Paper
Jul 2, 2026 0
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