Blocking Telomere Damage Signals Restores Blood Stem Cell Function in Aging
A targeted RNA therapy reverses hematopoietic decline in aged mice and human stem cells by silencing a key telomere-driven damage pathway.
4,573 articles in this topic
A targeted RNA therapy reverses hematopoietic decline in aged mice and human stem cells by silencing a key telomere-driven damage pathway.
A newly identified protein in blood vessel walls slows vascular aging in mice — and gene therapy targeting it shows promising results.
A 2025 meta-analysis of 12 RCTs confirms berberine meaningfully improves key metabolic syndrome markers with a favorable safety profile.
New research shows CD38 fuels epithelial ovarian cancer progression via PI3K-AKT and IL-6 pathways, while a CD38 inhibitor curbs tumor growth and immune suppression.
A comprehensive review of parathyroid hormone analogs reveals expanding therapeutic roles in osteoporosis, hypoparathyroidism, and fracture healing.
A major review clarifies how to identify and manage T2-low asthma, a poorly understood subtype lacking standard biomarkers and biologics.
A comprehensive 2025 review redefines hypereosinophilia classification and evaluates emerging biologics alongside established treatments for this complex multiorgan disorder.
Estrogen decline during menopause disrupts hair follicle function, raising risk of multiple hair loss conditions with real mental health consequences.
A comprehensive 2025 review maps the mechanisms behind MSC senescence and surveys emerging rejuvenation strategies for cell-based therapies.
A scoping review of 39 studies finds High-Intensity Functional Training drives major aerobic and strength gains, with psychobiological benefits too.
A landmark invasive study reveals that muscle pumping capacity is equal between sexes, but lower hemoglobin drives the VO2 max gap.
A 24-study meta-analysis finds adding blood flow restriction to interval training meaningfully improves VO2max, muscle strength, and endurance performance.