Advanced Therapies

4,573 articles in this topic

Blocking Telomere Damage Signals Restores Blood Stem Cell Function in Aging
Longevity & Aging

Blocking Telomere Damage Signals Restores Blood Stem Cell Function in Aging

A targeted RNA therapy reverses hematopoietic decline in aged mice and human stem cells by silencing a key telomere-driven damage pathway.

Research Paper
Jul 2, 2026 0
LRRC8A Protein Shields Blood Vessels From Aging Via AMPK-SIRT1 Pathway
Longevity & Aging

LRRC8A Protein Shields Blood Vessels From Aging Via AMPK-SIRT1 Pathway

A newly identified protein in blood vessel walls slows vascular aging in mice — and gene therapy targeting it shows promising results.

Research Paper
Jul 1, 2026 0
Berberine Cuts Triglycerides, Blood Sugar, and Waist Size in Metabolic Syndrome
Longevity & Aging

Berberine Cuts Triglycerides, Blood Sugar, and Waist Size in Metabolic Syndrome

A 2025 meta-analysis of 12 RCTs confirms berberine meaningfully improves key metabolic syndrome markers with a favorable safety profile.

Research Paper
Jul 1, 2026 0
CD38 Drives Ovarian Cancer Growth and Reshapes Its Immune Microenvironment
Longevity & Aging

CD38 Drives Ovarian Cancer Growth and Reshapes Its Immune Microenvironment

New research shows CD38 fuels epithelial ovarian cancer progression via PI3K-AKT and IL-6 pathways, while a CD38 inhibitor curbs tumor growth and immune suppression.

Research Paper
Jul 1, 2026 0
PTH-Based Medicines Reshape Bone Health Treatment for Osteoporosis and Beyond
Longevity & Aging

PTH-Based Medicines Reshape Bone Health Treatment for Osteoporosis and Beyond

A comprehensive review of parathyroid hormone analogs reveals expanding therapeutic roles in osteoporosis, hypoparathyroidism, and fracture healing.

Research Paper
Jul 1, 2026 0
T2-Low Asthma Gets a Roadmap for Diagnosis and Targeted Treatment
Longevity & Aging

T2-Low Asthma Gets a Roadmap for Diagnosis and Targeted Treatment

A major review clarifies how to identify and manage T2-low asthma, a poorly understood subtype lacking standard biomarkers and biologics.

Research Paper
Jul 1, 2026 0
Hypereosinophilia in 2025: New Classification Systems and Expanding Biologic Therapies
Longevity & Aging

Hypereosinophilia in 2025: New Classification Systems and Expanding Biologic Therapies

A comprehensive 2025 review redefines hypereosinophilia classification and evaluates emerging biologics alongside established treatments for this complex multiorgan disorder.

Research Paper
Jul 1, 2026 0
How Menopause Drives Hair Loss Through Hormonal Shifts
Longevity & Aging

How Menopause Drives Hair Loss Through Hormonal Shifts

Estrogen decline during menopause disrupts hair follicle function, raising risk of multiple hair loss conditions with real mental health consequences.

Research Paper
Jul 1, 2026 0
How Stem Cell Aging Works and What Scientists Are Doing to Reverse It
Longevity & Aging

How Stem Cell Aging Works and What Scientists Are Doing to Reverse It

A comprehensive 2025 review maps the mechanisms behind MSC senescence and surveys emerging rejuvenation strategies for cell-based therapies.

Research Paper
Jul 1, 2026 0
HIFT Boosts VO2max by Up to 15% and Strength by 20% for Hybrid Sport Athletes
Longevity & Aging

HIFT Boosts VO2max by Up to 15% and Strength by 20% for Hybrid Sport Athletes

A scoping review of 39 studies finds High-Intensity Functional Training drives major aerobic and strength gains, with psychobiological benefits too.

Research Paper
Jul 1, 2026 0
Why Females Have Lower VO2 Max Than Males — Hemoglobin Is the Key
Longevity & Aging

Why Females Have Lower VO2 Max Than Males — Hemoglobin Is the Key

A landmark invasive study reveals that muscle pumping capacity is equal between sexes, but lower hemoglobin drives the VO2 max gap.

Research Paper
Jul 1, 2026 0
Blood Flow Restriction Boosts Interval Training Results Across Key Fitness Markers
Longevity & Aging

Blood Flow Restriction Boosts Interval Training Results Across Key Fitness Markers

A 24-study meta-analysis finds adding blood flow restriction to interval training meaningfully improves VO2max, muscle strength, and endurance performance.

Research Paper
Jul 1, 2026 0
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