iTTP Survival Jumps From Near Zero to 93% With Modern Treatment Trio
A 2025 JAMA review breaks down how plasma exchange, rituximab, and caplacizumab transformed survival in this rare blood-clotting emergency.
3258 articles in this topic
A 2025 JAMA review breaks down how plasma exchange, rituximab, and caplacizumab transformed survival in this rare blood-clotting emergency.
RA patients show accelerated immune aging in T cells, B cells, and myeloid cells—predating joint inflammation and directly fueling autoimmunity.
New research reveals autophagy's dual role in ferroptosis—sometimes triggering cell death, sometimes preventing it—depending on iron, lipid, and radical levels.
The Break Wave device shatters kidney stones into passable fragments in 7 of 10 patients, no anesthesia needed, in a clinic setting.
Health groups disagree on when to start mammograms. Here's how to navigate conflicting screening guidelines and make an informed decision.
Engineered nanoparticles cleared 50-60% of toxic amyloid plaques within 1 hour and restored the blood-brain barrier in Alzheimer's mice.
A completed Phase 2 trial investigates the immune mechanisms behind age-related vaccine failure in older adults.
Most genetic tests are probabilistic, not deterministic. Attia explains when DNA data truly changes decisions and when it just adds noise.
A comprehensive review reveals how the enzyme CD38 drives cardiovascular and neurological disease through calcium, NAD+, and inflammation signaling.
Chronic NAD depletion causes mitochondrial DNA to escape into the cytoplasm, activating an interferon response that mimics a viral infection.
A novel immune cell subset, CD38-high monocytes, spikes within 24 hours of sepsis onset and may serve as both a diagnostic marker and drug target.
A specialized immune cell population near adipose nerves declines with age, fueling inflammaging and disrupting fat metabolism.