3258 articles in this topic
Cholecystokinin prevents microglia from pruning excitatory synapses in sepsis brain injury, pointing to new cognitive protection strategies.
Nephropathic Cystinosis alters serum N-glycosylation patterns, especially sialylation, offering potential new disease biomarkers.
The FAIR-HF2 trial tested intravenous ferric carboxymaltose in iron-deficient heart failure patients, with surprising results for hard clinical endpoints.
A comprehensive 2025 review reveals how AMPK orchestrates mitochondrial fission, mitophagy, and biogenesis to restore cellular energy homeostasis.
GLP-1 receptor agonists like semaglutide activate AMPK signaling to reduce amyloid plaques and restore memory in Alzheimer's mouse models.
A lysosome-to-epigenome pathway in C. elegans extends lifespan across multiple generations via histone H3.3 transport from gut to germline.
New research reveals how when you eat reshapes adipocyte signaling to boost endurance — and identifies a druggable target to mimic the effect.
A new study reveals that too much or too little Wnt signaling disrupts cilia formation, with mTOR inhibition rescuing the defect.
A 2026 review maps the molecular architecture of telomerase across four model organisms, illuminating cancer and aging disease mechanisms.
Middle-aged marathon runners showed 2.06-fold higher hTERT expression and significant cardiac adaptations compared to inactive controls.
Scientists find bowhead whale cells repair DNA damage faster and more accurately than other mammals, offering clues to extreme longevity.
Single-cell and spatial transcriptomics reveal how excess iron triggers cellular senescence and metabolic dysfunction in ovarian follicles, explaining poor oocyte quality in endometriosis.
