Longevity & Aging
Blue Zones Under the Microscope β Does the Science Actually Hold Up
Eric Topol and colleagues question whether blue zone longevity data is real or a statistical mirage worth rethinking.
Press Release
May 17, 2026 0
Reversing Aging
2910 articles in this topic
Longevity & Aging
Silent Tooth Infections May Sabotage Blood Sugar and Whole-Body Health
Hidden root infections trigger chronic inflammation that disrupts insulin function β and treating them may improve metabolic health.
Press Release
May 17, 2026 0
Longevity & Aging
Forever Healthy Launches Open-Source AI Tool to Evaluate Longevity Interventions
AI4L uses 'Audit-Driven Prompting' to generate hallucination-free, evidence-based reviews of longevity therapies like senolytics and NAD+ boosters.
Press Release
May 17, 2026 0
Longevity & Aging
How Your Immune System Ages and the Biomarkers That Reveal It
A comprehensive 2025 review maps the molecular and cellular mechanisms driving immune aging, from SASP to epigenetic drift.
Research Paper
May 17, 2026 0
Longevity & Aging
Immunosenescence Before COVID-19 Infection Drives Severe Disease Risk
Pre-existing immune aging signatures β not just chronological age β predict who progresses to severe COVID-19, new research shows.
Research Paper
May 17, 2026 0
Longevity & Aging
Dapagliflozin Blocks Kidney Cell Death in Diabetes via Ketone Body Pathway
SGLT2 inhibitor dapagliflozin protects diabetic kidneys by raising Ξ²-hydroxybutyrate and suppressing iron-driven cell death (ferroptosis).
Research Paper
May 16, 2026 0
Longevity & Aging
TRIM28 Fuels Kidney Cancer Immune Escape by Draining NAD+ and Boosting PD-L1
A newly uncovered TRIM28-PARP1 axis depletes NAD+ in tumors and T cells, enabling immune evasion in clear cell renal cell carcinoma.
Research Paper
May 16, 2026 0
Longevity & Aging
Blocking CD38 Revives Exhausted T Cells and Breaks Immunotherapy Resistance
A new study shows targeting CD38 in melanoma restores T cell energy metabolism and overcomes resistance to immune checkpoint therapies.
Research Paper
May 16, 2026 0
Longevity & Aging
Physical Compression Kills Cells via Ferroptosis Triggered by Mitochondrial Collapse
Researchers reveal how mechanical confinement deforms the cell nucleus, fractures mitochondria, and ignites iron-driven cell deathβwith implications for osteoarthritis.
Research Paper
May 16, 2026 0
Longevity & Aging
How Brain Iron Shapes Development, Aging, and Neurodegeneration
A comprehensive review reveals how iron homeostasis governs brain health from infancy through old age and drives Alzheimer's and Parkinson's disease.
Research Paper
May 16, 2026 0
Longevity & Aging
Lymphoma Forces Young T Cells to Age Decades in Just Days
B cell lymphoma rapidly drives young T cells into a molecular and epigenetic aged state, while truly old T cells prove strangely resistant.
Research Paper
May 16, 2026 0
Longevity & Aging
How Cancer Cells Die Shapes Immunity and Treatment Durability
New review reveals how different cancer cell death pathwaysβfrom ferroptosis to pyroptosisβdetermine whether tumors fuel or suppress immune responses.
Research Paper
May 16, 2026 0