Women's Midlife Is the Critical Window for Alzheimer Prevention
Two-thirds of Alzheimer cases are women. New evidence shows menopause transition—not just aging—drives that risk, opening a prevention window.
975 articles in this topic
Two-thirds of Alzheimer cases are women. New evidence shows menopause transition—not just aging—drives that risk, opening a prevention window.
A single phosphorylation site on clock protein PER2, triggered by dietary fat, controls how fast mice synchronize to seasonal light cycles.
New research links multimorbidity — especially cardiometabolic disease clusters — to measurable brain-age acceleration in dementia-free older adults.
New research reveals how lipid droplets spark the protein aggregation at the heart of Parkinson's disease, disrupting energy metabolism.
Older adults with higher cardiorespiratory fitness had ~48% lower Alzheimer's risk over 8.7 years, with a clear VO2 threshold identified.
Two small clinical trials show BCG vaccination alters immune activity in cerebrospinal fluid and changes amyloid-β levels in older adults.
A Canadian RCT tests whether virtual aerobic, resistance, and cognitive training can feasibly combat mild cognitive impairment at home.
High-intensity home cycling improved ataxia symptoms, fatigue, and VO2max significantly more than dose-matched balance training over one year.
A pilot RCT tests whether the SysLife© app can reduce subjective stress and improve functioning in work and personal life.
A large-scale genomic study identifies 39 shared genetic loci between schizophrenia and Alzheimer's disease, converging on chromosome 16p11.2.
A nested study within the PREDIMED trial finds elevated resistin — an adipose-derived hormone — associated with 56% higher odds of incident Alzheimer's disease.
A 30-study review finds exercise and mindfulness alter resting brain connectivity, but the largest rigorous trial shows minimal effects.