982 articles in this topic
A global consortium reveals how tube type, delays, and storage temperature dramatically skew key Alzheimer's blood biomarker readings.
A novel Aβ1-10 peptide vaccine conjugated to carrier proteins reduced plaques, neuroinflammation, and memory deficits in an AD mouse model.
New review links HCMV — infecting up to 100% of adults — to Alzheimer's pathology, tau tangles, and accelerated cognitive decline.
A UCLA mouse study identifies the specific prefrontal neuron type responsible for TMS's fast-acting antidepressant action.
New research reveals APOE2, the longevity-linked gene variant, shields human neurons from aging damage through enhanced DNA repair — not just lipid metabolism.
A machine-learning model using 39 cardiovascular and autonomic variables predicted cognitive test performance with ~71% accuracy in healthy adults.
A 38-year Finnish cohort study finds higher lifelong physical activity protects information processing and working memory into midlife.
A completed RCT tested whether a CBT-based smartphone app reduces moderate depression versus an active placebo in 158 participants; outcomes are not reported in the registration record.
A completed pilot trial tested humanoid robots and AI predictive models to manage dementia care at home, personalizing treatment pathways.
A new Cell study reveals the fronto-insular circuit as the key mediator of TMS antidepressant effects, opening the door to optimized treatment.
New iPSC and cerebral organoid research shows HSV-1 directly activates neurodegeneration and senescence pathways, supporting the viral hypothesis of Alzheimer's disease.
Plasma p-tau217 accurately detects preclinical Alzheimer's in cognitively normal adults, potentially enabling earlier intervention.
