Cancer Research
FDA Approves Sonrotoclax for Hard-to-Treat Mantle Cell Lymphoma
Sonrotoclax (Beqalzi), a next-gen BCL-2 inhibitor, wins accelerated FDA approval for relapsed or refractory MCL after BTK inhibitor failure.
Drug Approval
May 15, 2026 0
Cancer
506 articles in this topic
Cancer Research
Hepatitis Viruses Drive Three-Quarters of Global Liver Cancer Cases
A massive 857-study meta-analysis maps hepatitis B and C contributions to liver cancer across 81 countries, revealing stark regional disparities.
Research Paper
May 15, 2026 0
Cancer Research
PULSAR Radiation Plus IMSA101 Immunotherapy Trial in Oligoprogressive Cancers Terminated Early
A Phase 2 trial combining adaptive stereotactic radiotherapy with IMSA101 and checkpoint inhibitors was halted after enrolling only 16 patients.
Clinical Trial
May 14, 2026 0
Cancer Research
Pfizer Terminates Phase 1 Trial of Novel Anti-PD-1/IL-15 Fusion Protein in Solid Tumors
Pfizer's first-in-human trial of PF-07209960, a dual-action immunotherapy fusion protein, was terminated after enrolling 37 patients.
Clinical Trial
May 14, 2026 0
Cancer Research
Personalized DNA Cancer Vaccine Shows Promise Against Deadly Brain Tumors
A phase 1 trial of a neoantigen DNA vaccine for glioblastoma found strong immune responses and survival rates exceeding historical benchmarks.
Research Paper
May 14, 2026 0
Cancer Research
Myeloid Cell Plasticity Emerges as a Key Target for Next-Gen Cancer Therapies
A new review reframes how myeloid cells fuel or fight tumors, pointing to plasticity — not just cell diversity — as the core therapeutic target.
Review
May 14, 2026 0
Cancer Research
Nivolumab Fails to Outperform Durvalumab in Stage III Lung Cancer Trial
A phase 3 trial finds nivolumab-based regimens offer no survival advantage over durvalumab for unresectable stage III NSCLC.
Research Paper
May 14, 2026 0
Cancer Research
Enzyme AARS2 Hijacks Lactate to Drive Liver Cancer and Becomes a Drug Target
A newly identified enzyme links lactate metabolism to liver cancer progression, and a natural compound delivered via nanoparticles shows striking anti-tumor results.
Research Paper
May 14, 2026 0
Cancer Research
Urine Test May Soon Track Senescent Cells in Cancer and Fibrosis
Cambridge scientists engineer a nanoprobe that detects therapy-induced senescence non-invasively through a simple urine colorimetric test.
Research Paper
May 14, 2026 0
Cancer Research
New Senolytic Drugs Force Cancer's Zombie Cells to Self-Destruct
Scientists found drugs that kill senescent 'zombie cells' by blocking their key survival protein, shrinking tumors in mice.
Press Release
May 13, 2026 0
Cancer Research
FDA Approves Zenocutuzumab-zbco for Advanced Cholangiocarcinoma
The FDA approved zenocutuzumab-zbco for adults with advanced, unresectable, or metastatic cholangiocarcinoma, a rare and aggressive bile duct cancer with limited treatment options.
Drug Approval
May 13, 2026 0
Cancer Research
Amgen's PSMA Bispecific T-Cell Engager Acapatamab Tested in Advanced Prostate Cancer
Phase 1 trial of acapatamab, a PSMA-targeting bispecific T-cell engager, enrolls 212 men with metastatic castration-resistant prostate cancer.
Clinical Trial
May 13, 2026 0