Heart Disease

518 articles in this topic

Gaps in Post-Heart Attack Care Are Leaving Millions of Americans Unprotected
Heart Health

Gaps in Post-Heart Attack Care Are Leaving Millions of Americans Unprotected

A major JACC study exposes how secondary prevention after myocardial infarction falls short across the U.S. population.

Research Paper
May 12, 2026 0
Epicardial Fat Radiomics Could Transform Heart Failure Risk Prediction
Heart Health

Epicardial Fat Radiomics Could Transform Heart Failure Risk Prediction

AI-driven analysis of fat surrounding the heart may unlock a powerful new tool for predicting heart failure before symptoms emerge.

Research Paper
May 12, 2026 0
Earlier Evolocumab Use Linked to Lower Arterial Aneurysm Risk in Major Trial
Heart Health

Earlier Evolocumab Use Linked to Lower Arterial Aneurysm Risk in Major Trial

FOURIER and FOURIER-OLE data suggest that earlier initiation of the PCSK9 inhibitor evolocumab may reduce arterial aneurysm events.

Research Paper
May 12, 2026 0
Low-Dose Digoxin Fails to Reduce Heart Failure Events in Major RCT
Heart Health

Low-Dose Digoxin Fails to Reduce Heart Failure Events in Major RCT

The DECISION trial finds low-dose digoxin did not significantly cut hospitalizations or cardiovascular death in 1,001 HFrEF/HFmrEF patients.

Research Paper
May 12, 2026 0
miR-132 Inhibitor CDR132L Misses Primary Endpoint in Post-MI Heart Failure Trial
Heart Health

miR-132 Inhibitor CDR132L Misses Primary Endpoint in Post-MI Heart Failure Trial

A phase 2 trial of the microRNA-132 inhibitor CDR132L showed safety but no significant improvement in cardiac remodeling after heart attack.

Research Paper
May 12, 2026 0
Senolytics, Gene Therapy and Lifestyle Can Slow Cardiovascular Aging
Heart Health

Senolytics, Gene Therapy and Lifestyle Can Slow Cardiovascular Aging

A 2025 review maps the molecular drivers of cardiac aging and evaluates drugs, CRISPR, stem cells, and lifestyle as countermeasures.

Research Paper
May 11, 2026 0
Sacubitril/Valsartan Improves Exercise Capacity in HFpEF with Mitral Regurgitation
Heart Health

Sacubitril/Valsartan Improves Exercise Capacity in HFpEF with Mitral Regurgitation

The PRAISE-MR trial finds sacubitril/valsartan significantly improves exercise hemodynamics and quality of life in a high-risk HFpEF phenotype.

Research Paper
May 11, 2026 0
Digitalis Revisited: Old Heart Drug Cuts HF Hospitalizations by 25%
Heart Health

Digitalis Revisited: Old Heart Drug Cuts HF Hospitalizations by 25%

A JAMA meta-analysis of 9,000+ patients finds digitalis glycosides significantly reduce worsening heart failure events, reigniting interest in a centuries-old drug.

Research Paper
May 11, 2026 0
How Chronic Inflammation Drives Heart Aging and What Can Stop It
Heart Health

How Chronic Inflammation Drives Heart Aging and What Can Stop It

A comprehensive review reveals how inflammaging—the fusion of aging and inflammation—fuels cardiovascular disease through senescence, mitochondrial dysfunction, and gut dysbiosis.

Research Paper
May 10, 2026 0
Syphilis Infection Tied to Elevated Risk of Serious Cardiovascular Events
Heart Health

Syphilis Infection Tied to Elevated Risk of Serious Cardiovascular Events

New JAMA research links syphilis infection to a meaningfully higher risk of certain cardiovascular outcomes, raising screening urgency.

Research Paper
May 10, 2026 0
Wearable Heart Sensor May Replace Treadmill Tests for Measuring Fitness Age
Heart Health

Wearable Heart Sensor May Replace Treadmill Tests for Measuring Fitness Age

A completed trial tested whether seismocardiography can accurately estimate VO2max and biological age without exhaustive exercise testing.

Clinical Trial
May 9, 2026 0
Angina Threshold for PCI Is Far Lower Than Current Diagnostic Cutoffs
Heart Health

Angina Threshold for PCI Is Far Lower Than Current Diagnostic Cutoffs

ORBITA-FIRE reveals personalized physiological angina thresholds are dramatically lower than the universal FFR/RFR values used to guide stent decisions.

Research Paper
May 9, 2026 0
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