Advanced Therapies

4,593 articles in this topic

First Patient Dosed in ALS Gene-Targeting Trial Using Sphingolipid Therapy
Longevity & Aging

First Patient Dosed in ALS Gene-Targeting Trial Using Sphingolipid Therapy

Leal Therapeutics launches first-in-human trial of LTX-002, an antisense drug targeting toxic lipid buildup in ALS motor neurons.

Press Release
Jun 26, 2026 0
NorthStrive Patents Muscle-Preservation Tech to Pair With GLP-1 Weight Loss Drugs
Longevity & Aging

NorthStrive Patents Muscle-Preservation Tech to Pair With GLP-1 Weight Loss Drugs

NorthStrive Biosciences files patents targeting muscle loss — a major side effect of GLP-1 obesity drugs — using peptide and microbiome tech.

Press Release
Jun 26, 2026 0
Primate-Specific RNA Molecule Drives Aging by Destabilizing Key Cellular Proteins
Longevity & Aging

Primate-Specific RNA Molecule Drives Aging by Destabilizing Key Cellular Proteins

A newly identified lncRNA found only in primates accelerates cellular senescence and aging-like decline via a novel RNA-protein pathway.

Research Paper
Jun 26, 2026 0
How Sugar Ages Your Skin: The Hidden Role of Glycation in Skin Aging
Longevity & Aging

How Sugar Ages Your Skin: The Hidden Role of Glycation in Skin Aging

AGEs silently degrade collagen and elastin, accelerating wrinkles and laxity. New diagnostics and therapies are emerging to fight back.

Research Paper
Jun 25, 2026 0
Gold Nanocages Deliver Dual-Action Antidepressant Payload Deep Into the Brain
Longevity & Aging

Gold Nanocages Deliver Dual-Action Antidepressant Payload Deep Into the Brain

A novel nanoparticle combining NAC antioxidant capping with the neuropeptide TLQP21 reverses depression-like behavior in stressed mice.

Research Paper
Jun 25, 2026 0
SENP1-Sirt3 Axis Shields Lung Stem Cells from Oxidative Damage and Fibrosis
Longevity & Aging

SENP1-Sirt3 Axis Shields Lung Stem Cells from Oxidative Damage and Fibrosis

A newly identified mitochondrial pathway protects alveolar stem cells from oxidative stress, cutting fibrosis and inflammation in mouse lung injury models.

Research Paper
Jun 25, 2026 0
Bacterial Toxin Mimics Human CD38 to Deplete NAD+ in Rivals and Host Cells
Longevity & Aging

Bacterial Toxin Mimics Human CD38 to Deplete NAD+ in Rivals and Host Cells

Scientists discover a bacterial weapon structurally identical to human CD38 that drains NAD+ — a molecule central to aging and cellular energy.

Research Paper
Jun 25, 2026 0
Integrative Strategies Help Women Thrive Through Perimenopause
Longevity & Aging

Integrative Strategies Help Women Thrive Through Perimenopause

A new review outlines how diet, movement, supplements, and hormone therapy combine to ease perimenopause and support long-term healthy aging.

Research Paper
Jun 25, 2026 0
The Menopause Transition Accelerates Aging Markers Before Periods Even Stop
Longevity & Aging

The Menopause Transition Accelerates Aging Markers Before Periods Even Stop

New review reveals the perimenopause window is when metabolic, cardiovascular, and bone health shift most dramatically — not after.

Research Paper
Jun 25, 2026 0
Fisetin Reverses Chemo-Induced Vascular Aging by Clearing Senescent Cells
Longevity & Aging

Fisetin Reverses Chemo-Induced Vascular Aging by Clearing Senescent Cells

A natural flavonoid found in fruits clears senescent cells and restores artery function damaged by doxorubicin chemotherapy in mice.

Research Paper
Jun 25, 2026 0
Stem Cell Therapy Offers New Hope for Restoring Fertility in Uterine Disorders
Longevity & Aging

Stem Cell Therapy Offers New Hope for Restoring Fertility in Uterine Disorders

Mesenchymal stem cells and their exosomes show strong promise for repairing endometrial damage caused by intrauterine adhesions and endometriosis.

Research Paper
Jun 25, 2026 0
Stem Cell Therapy Offers New Hope for Systemic Sclerosis Patients
Longevity & Aging

Stem Cell Therapy Offers New Hope for Systemic Sclerosis Patients

A 2025 review evaluates autologous HSC transplantation and mesenchymal stem cells as transformative treatments for systemic sclerosis.

Research Paper
Jun 25, 2026 0
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