New Approach Reactivates Mutant p53 Tumor Suppressor in Cancer Patients
Researchers develop selective method to restore function of mutated p53 protein, potentially offering new cancer treatment strategy.
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Researchers develop selective method to restore function of mutated p53 protein, potentially offering new cancer treatment strategy.
Massive study reveals cancer mutations behave differently across tissue types, challenging gene-focused treatment approaches.
ASTER 70s trial compares treatment intensities for women 70+ with genomically high-risk breast cancer to optimize outcomes while minimizing toxicity.
Novel nanoparticle combines protein degrader with light therapy to reprogram cancer metabolism and eliminate breast tumors.
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Phase 1/2 umbrella trial matches glioblastoma patients to targeted treatments based on tumor genetics, with temsirolimus showing significant benefit.
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Scientists develop LP-65, a single molecule targeting two cancer pathways simultaneously, showing enhanced anti-tumor effects in lab studies.
New study reveals how blocking ribosome production makes cancer cells vulnerable to ferroptosis, an iron-dependent cell death pathway.
New research reveals how a cancer-promoting protein reprograms cellular fat production to accelerate tumor progression.