Combination SMA Therapy Shows Promise: Gene Therapy Plus Oral Drug Improves Outcomes
Real-world study of 20 children shows adding risdiplam after gene therapy improved motor, breathing, and swallowing function in spinal muscular atrophy.
1427 articles in this topic
Real-world study of 20 children shows adding risdiplam after gene therapy improved motor, breathing, and swallowing function in spinal muscular atrophy.
Clinical trial finds standard HPV vaccination significantly reduces actinic keratosis burden in adults with multiple lesions.
Comprehensive analysis of 14 trials reveals RSV vaccines reduce respiratory illness by up to 77% in older adults and 74% in infants through maternal vaccination.
Machine learning approach combining plasma biomarkers with traditional risk factors improves cardiovascular disease prediction and risk stratification.
Scientists identify blood biomarkers from aging immune cells that predict mobility, metabolism, and body composition changes in over 1,000 adults.
Mathematical modeling shows high-risk HPV testing with increased vaccination rates could achieve cervical cancer elimination by 2034 in South Korea.
Large-scale study of 131,821 people finds moderate caffeinated coffee consumption significantly reduces dementia risk and improves cognitive function.
Large trial finds tirzepatide as safe as dulaglutide for heart outcomes in type 2 diabetes patients with existing cardiovascular disease.
New research reveals how oral microbiome imbalances trigger neurodegeneration through redox signaling and inflammation.
Meta-analysis reveals distinct oral bacteria patterns in autism, schizophrenia, depression and other mental disorders.
Large study reveals how raising different farm animals changes the bacterial communities in farmers' mouths, with implications for disease risk.
Large community study reveals how periodontal disease and oral bacteria may accelerate brain aging through inflammatory pathways.