Naked Mole-Rats Use cGAS Pathway to Supercharge DNA Repair and Slow Aging
New research reveals how naked mole-rats activate a unique DNA repair mechanism that may explain their extraordinary longevity.
4318 articles
New research reveals how naked mole-rats activate a unique DNA repair mechanism that may explain their extraordinary longevity.
Comprehensive review reveals how telomerase biogenesis regulates telomere maintenance, offering new therapeutic targets for aging disorders.
Comprehensive review reveals promising new drug targets and immunotherapy approaches for myelofibrosis beyond current JAK inhibitor limitations.
New review reveals how damaged mitochondria accelerate aging through metabolic reprogramming, inflammation, and cellular dysfunction.
New structural insights show how telomerase enzymes pair up through H/ACA RNA complexes, advancing our understanding of cellular aging mechanisms.
Comprehensive review reveals glioblastoma's devastating prognosis with only 5.5% five-year survival rate and key genetic markers for treatment.
Comprehensive review reveals how parabiosis, organoids, and assembloids complement each other to model complex diseases from systemic to tissue levels.
Breakthrough skin organoids contain blood vessels, hair follicles, and immune cells, opening new paths for disease modeling and regenerative medicine.
Researchers outline vision for fully automated bioprinting laboratories that use AI and robotics to manufacture tissues and organs with minimal human intervention.
Vascular-inspired scaffolds solve oxygen diffusion problems in brain organoids, enabling better drug testing models.
NHANES analysis reveals Mediterranean, DASH, and HEI diets significantly reduce biological aging acceleration through anti-aging proteins.
Ganoderma lucidum spore powder extended lifespan and increased ฮฑ-Klotho levels across organs in worms and mice aging models.