Artificial Corneas Are Restoring Sight Where Transplants Fail
A comprehensive review of keratoprosthesis devices and bioengineered corneal therapies offering hope for end-stage corneal blindness.
420 articles in this topic
A comprehensive review of keratoprosthesis devices and bioengineered corneal therapies offering hope for end-stage corneal blindness.
Stem cell-derived fibroblasts partially adopt organ-specific transcriptional profiles when co-cultured with heart, skin, gut, or lung cells — with key implications for disease modelling.
A comprehensive review of cell-based therapies and engineered biomaterials for SCI, covering ESCs, MSCs, NSCs, and scaffold strategies.
A Phase 1/2 trial of NFS-02 gene therapy for LHON-associated vision loss was terminated before completion, raising questions about mitochondrial gene therapy.
Phase 3 data show exa-cel eliminated transfusions and vaso-occlusive crises in children ages 5–11 with serious inherited blood disorders.
A Cell study reveals why ~50% of fertilized human eggs arrest, identifying two independent molecular culprits at different developmental stages.
Emerging neurotech approaches are shifting focus from failed drug targets toward gene therapy, bioelectronics, and AI-guided diagnostics.
A new class of cancer drugs targets replication stress — a core vulnerability in tumor cells — potentially opening a long-sought therapeutic window.
A completed multicenter feasibility trial evaluates BTM, a novel biodegradable scaffold, for treating serious deep burn injuries.
Scientists achieve first precise genome editing of human embryos, drawing both acclaim and ethical concern from the scientific community.
Researchers identify how host macrophages destroy foreign cells in embryos — and three strategies to stop it, boosting organ-growing chimeras.
New ESHRE guidelines define best practices for testicular tissue cryopreservation in children facing gonadotoxic therapies, covering eligibility, counselling, and biopsy protocols.