Advanced Therapies

1687 articles in this topic

New CRISPR-Spatial Method Maps Gene Networks in Living Tissues
Longevity & Aging

New CRISPR-Spatial Method Maps Gene Networks in Living Tissues

Perturb-FISH combines CRISPR screening with spatial gene mapping to reveal how cells communicate and respond to genetic changes.

Research Paper
Mar 31, 2026 0
AI System Automates CRISPR Gene Editing Experiments from Design to Analysis
Longevity & Aging

AI System Automates CRISPR Gene Editing Experiments from Design to Analysis

CRISPR-GPT uses large language models to guide researchers through complex gene editing workflows, successfully demonstrating automated knockout and activation experiments.

Research Paper
Mar 31, 2026 0
CRISPR Gene Activation Rescues Severe Neurodevelopmental Disorders in Mice
Longevity & Aging

CRISPR Gene Activation Rescues Severe Neurodevelopmental Disorders in Mice

Breakthrough study shows CRISPR activation can restore brain function in genetic disorders by boosting remaining healthy gene copies.

Research Paper
Mar 31, 2026 0
CRISPR Screen Reveals New Target to Boost Regulatory T Cell Therapy for Autoimmune Disease
Longevity & Aging

CRISPR Screen Reveals New Target to Boost Regulatory T Cell Therapy for Autoimmune Disease

Scientists identify RBPJ protein as key brake on regulatory T cells, opening path to more effective autoimmune treatments.

Research Paper
Mar 31, 2026 0
CRISPR Technology Advances Enable Precise Gene Editing for Longevity Research
Longevity & Aging

CRISPR Technology Advances Enable Precise Gene Editing for Longevity Research

Comprehensive review reveals how CRISPR innovations are revolutionizing genome editing with enhanced precision and safety for therapeutic applications.

Research Paper
Mar 31, 2026 0
CRISPR Screens Identify Gene Targets to Supercharge Cancer-Fighting NK Cells
Longevity & Aging

CRISPR Screens Identify Gene Targets to Supercharge Cancer-Fighting NK Cells

Genome-wide CRISPR screening reveals three key genes that, when knocked out, dramatically enhance NK cell therapy against cancer.

Research Paper
Mar 31, 2026 0
Scientists Discover New RNA-Guided Gene Editing System in Viruses and Bacteria
Longevity & Aging

Scientists Discover New RNA-Guided Gene Editing System in Viruses and Bacteria

Researchers identify TIGR-Tas systems that could expand genome editing capabilities beyond CRISPR technology.

Research Paper
Mar 31, 2026 0
Exercise Reverses Cellular Aging in Muscle, Restoring Insulin Sensitivity
Longevity & Aging

Exercise Reverses Cellular Aging in Muscle, Restoring Insulin Sensitivity

New study shows physical training reduces senescent cells in skeletal muscle and improves metabolic function in both lean and obese individuals.

Research Paper
Mar 31, 2026 0
New Targeted Drug Platform Eliminates Aging Cells While Avoiding Toxic Side Effects
Longevity & Aging

New Targeted Drug Platform Eliminates Aging Cells While Avoiding Toxic Side Effects

Scientists develop mGL392, a precision senolytic that targets aging cells using lipofuscin binding while minimizing systemic toxicity.

Research Paper
Mar 31, 2026 0
Senolytic Drugs Show Promise and Peril for Heart Disease Treatment
Longevity & Aging

Senolytic Drugs Show Promise and Peril for Heart Disease Treatment

New review reveals senolytic therapies can both help and harm cardiovascular health, challenging clinical translation.

Research Paper
Mar 31, 2026 0
Senescent Cell Targeting Shows Promise for Treating Age-Related Lung Diseases
Longevity & Aging

Senescent Cell Targeting Shows Promise for Treating Age-Related Lung Diseases

Comprehensive review reveals how cellular senescence drives lung aging and disease, highlighting therapeutic potential of senolytics and senomorphics.

Research Paper
Mar 31, 2026 0
Scientists Identify Critical Cancer Cell State That Drives Lung Tumor Growth and Resistance
Longevity & Aging

Scientists Identify Critical Cancer Cell State That Drives Lung Tumor Growth and Resistance

Researchers discover a high-plasticity cell state that enables cancer progression and therapy resistance, offering new therapeutic targets.

Research Paper
Mar 31, 2026 0
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