Cancer Research
Blocking USP30 Revives Exhausted Cancer-Fighting T Cells
Scientists found that inhibiting USP30, a mitochondrial enzyme, restores immune cell function and shrinks tumors in mice.
Research Paper
Jun 22, 2026 0
Cancer
675 articles in this topic
Cancer Research
Blocking Haem Signaling Revives Exhausted Cancer-Fighting T Cells
Scientists identify a mitochondria-proteasome-haem pathway that silences immune cells — and show bortezomib can fix it in CAR-T therapy.
Research Paper
Jun 22, 2026 0
Cancer Research
Mitochondrial Power Determines How Well Immune Cells Fight Cancer
A new Science paper reveals that mitochondrial fitness in dendritic cells controls antitumor immunity — and can be targeted to boost immunotherapy.
Research Paper
Jun 22, 2026 0
Cancer Research
DNA Repair Gene EXO1 Goes Rogue and Reveals a Targetable Cancer Weakness
When the DNA-repair gene EXO1 is overproduced, it damages DNA instead of fixing it—exposing a hidden vulnerability in multiple cancers.
Press Release
Jun 21, 2026 0
Cancer Research
How Nerves Help Bile Duct Cancer Spread and Evade Immune Attack
A new review reveals how cholangiocarcinoma hijacks the nervous system to invade tissue and suppress immune defenses.
Research Paper
Jun 21, 2026 0
Cancer Research
Erratum Issued for 2022 Study on Cancer Cells Co-opting Nociceptive Nerves
Cell Metabolism has published an erratum (correction notice) for a 2022 paper reporting that cancer cells co-opt nociceptive nerves to survive nutrient stress.
Research Paper
Jun 21, 2026 0
Cancer Research
Myeloma Cells Can Permanently Lose CD38 to Escape Daratumumab Therapy
Genomic study reveals 20% of post-CD38-therapy myeloma patients show CD38 loss, including biallelic escape conferring permanent drug resistance.
Research Paper
Jun 20, 2026 0
Cancer Research
MD Anderson Tests Dual Checkpoint Blockade Plus Radiation for HPV Throat Cancer
A phase II trial explored ipilimumab, nivolumab, and radiation therapy in advanced HPV-positive oropharyngeal cancer — but was terminated early.
Clinical Trial
Jun 20, 2026 0
Cancer Research
TROP2 Targeting Delays Resistance to Lung Cancer Therapy in Preclinical Models
A new strategy combining a TROP2-targeting drug with osimertinib may delay the inevitable resistance that undermines EGFR-mutant lung cancer treatment.
Research Paper
Jun 19, 2026 0
Cancer Research
TROP2 Antibody-Drug Conjugates Target the Hidden Survivors of Lung Cancer Therapy
A new 'induce-target-kill' strategy uses TROP2-directed ADCs to eliminate drug-tolerant persister cells in EGFR-mutant lung cancer.
Research Paper
Jun 19, 2026 0
Cancer Research
Chronic Stress Fuels Glioma Growth Through Rogue Bone Marrow Macrophages
New research reveals how chronic stress recruits immunosuppressive macrophages from bone marrow into brain tumors, accelerating glioma progression.
Research Paper
Jun 19, 2026 0
Cancer Research
Poxvirus Cancer Vaccines Targeting CEA and MUC-1 Tested in Advanced Solid Tumors
A Phase 1/2 NCI trial tested PANVAC vaccinia and fowlpox vaccines plus immune booster sargramostim in advanced colorectal, breast, and ovarian cancers.
Clinical Trial
Jun 18, 2026 0