461 articles in this topic
A comprehensive 2025 review maps the metabolic chaos driving diabetic foot ulcers and evaluates emerging treatments from exosomes to gene therapy.
A novel mathematical model using deuterium MRI shows gastric bypass redirects nearly all ingested glucose through the liver, with more peripheral disposal.
A Phase 2 trial tests a GalNAc-conjugated antisense therapy in familial partial lipodystrophy patients with dangerously high triglycerides.
Dr. Mauricio Gonzalez argues we've been measuring the wrong thing — and explains how targeting liver fat changes everything about metabolic care.
A comprehensive 2025 review framework matches GLP-1 agonists, tirzepatide, and other AOMs to specific obesity phenotypes, complications, and life stages.
A 60-week RCT finds semaglutide 2.4 mg sustains ~240 kcal/day reduction even after appetite benefits diminish.
Tebipenem pivoxil becomes the first oral carbapenem approved in the US, offering a non-IV option for serious UTIs.
A completed trial investigates whether replenishing glutathione precursors can reverse metabolic dysfunction in elderly adults.
50 nm polystyrene nanoplastics accumulate in mouse testes, degrading sperm quality and triggering iron-dependent cell death through a newly identified mitochondrial pathway.
An erratum to a 2022 Cell Metabolism paper describing a bone marrow lipolytic factor that links mechanical force to bone formation and lymphocyte production.
Enanta Pharmaceuticals tests its FXR agonist EDP-305 in a completed Phase 2 randomized trial for non-alcoholic steatohepatitis.
A new perspective argues sedentary behavior independently impairs insulin sensitivity and metabolic function, upstream of obesity itself.
