Advanced Therapies

1741 articles in this topic

Aging and Injury Trigger Senescent Neurons in Pain-Processing Centers
Longevity & Aging

Aging and Injury Trigger Senescent Neurons in Pain-Processing Centers

Study reveals how aging and nerve injury create inflammatory senescent neurons in dorsal root ganglia, potentially driving chronic pain in older adults.

Research Paper
Mar 31, 2026 0
Neutrophils Show Surprising Plasticity That Could Transform Cancer Treatment
Longevity & Aging

Neutrophils Show Surprising Plasticity That Could Transform Cancer Treatment

New research reveals neutrophils can switch between cancer-fighting and cancer-promoting roles, opening therapeutic possibilities.

Research Paper
Mar 31, 2026 0
Oral Semaglutide Cuts Heart Disease Risk by 14% in High-Risk Diabetes Patients
Longevity & Aging

Oral Semaglutide Cuts Heart Disease Risk by 14% in High-Risk Diabetes Patients

Major trial shows oral diabetes drug significantly reduces cardiovascular events in nearly 10,000 high-risk patients over 4 years.

Research Paper
Mar 31, 2026 0
Nano-Adjuvant Reverses Age-Related Muscle Loss Through Mitochondrial Restoration
Longevity & Aging

Nano-Adjuvant Reverses Age-Related Muscle Loss Through Mitochondrial Restoration

Novel nanoparticle therapy targets sarcopenia by restoring mitochondrial function and enhancing muscle-immune cell communication.

Research Paper
Mar 31, 2026 0
Mitochondrial Cleanup Protein FUNDC1 Drives Nerve Regeneration After Injury
Longevity & Aging

Mitochondrial Cleanup Protein FUNDC1 Drives Nerve Regeneration After Injury

New research reveals how cellular cleanup of damaged mitochondria determines whether injured nerves can regrow and recover function.

Research Paper
Mar 31, 2026 0
Urolithin A Protects Against ALS Motor Dysfunction Through Mitochondrial Repair
Longevity & Aging

Urolithin A Protects Against ALS Motor Dysfunction Through Mitochondrial Repair

Study shows pomegranate compound urolithin A improves motor function in ALS mice by activating cellular cleanup of damaged mitochondria.

Research Paper
Mar 31, 2026 0
Mitophagy Drug Shows Promise Against ALS Motor Neuron Death
Longevity & Aging

Mitophagy Drug Shows Promise Against ALS Motor Neuron Death

Urolithin A activates cellular cleanup to protect motor neurons and improve movement in ALS mouse models.

Research Paper
Mar 31, 2026 0
Urolithin A Blocks Inflammatory Aging Signals by Targeting DNA Leakage in Senescent Cells
Longevity & Aging

Urolithin A Blocks Inflammatory Aging Signals by Targeting DNA Leakage in Senescent Cells

Pomegranate metabolite urolithin A reduces harmful inflammatory signals from aging cells by preventing DNA leakage and blocking cGAS-STING pathway.

Research Paper
Mar 31, 2026 0
Urolithin A Reverses Cognitive Decline in Parkinson's Disease Mouse Models
Longevity & Aging

Urolithin A Reverses Cognitive Decline in Parkinson's Disease Mouse Models

Natural compound from pomegranates and berries shows promise for treating cognitive symptoms in Parkinson's disease through brain protection.

Research Paper
Mar 31, 2026 0
Urolithin A Protects Female Fertility from Chemotherapy Damage
Longevity & Aging

Urolithin A Protects Female Fertility from Chemotherapy Damage

Gut metabolite preserves ovarian reserve by blocking harmful signaling pathways and preventing follicle death during cancer treatment.

Research Paper
Mar 31, 2026 0
Berry Compound Urolithin A Protects Tendon Cells from Fat-Induced Damage
Longevity & Aging

Berry Compound Urolithin A Protects Tendon Cells from Fat-Induced Damage

Natural compound from berries and nuts prevents tendon cell death and oxidative damage in obesity-related conditions.

Research Paper
Mar 31, 2026 0
Urolithin A Blocks Osteosarcoma Metastasis by Targeting Key Cancer Pathways
Longevity & Aging

Urolithin A Blocks Osteosarcoma Metastasis by Targeting Key Cancer Pathways

Natural compound urolithin A significantly inhibits bone cancer cell migration and invasion through AKT1 and MMP pathway modulation.

Research Paper
Mar 31, 2026 0
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