CAR T Cell Therapy Targets Mutant Calreticulin to Selectively Destroy Myelofibrosis Cells
A precision CAR T cell therapy wipes out disease-driving myelofibrosis stem cells while sparing healthy ones — a potential cure candidate.
4,573 articles in this topic
A precision CAR T cell therapy wipes out disease-driving myelofibrosis stem cells while sparing healthy ones — a potential cure candidate.
A liver-specific protein triggers aging not through cell death, but by spreading senescence via mitochondrial dysfunction and inflammatory signals.
New satellite data reveals the SAA's radiation boundaries are more dynamic than thought, posing wider spacecraft risks.
Researchers silenced nearly every expressed gene in human iPSCs, creating a landmark map of pluripotency's genetic architecture.
A new prime editing approach gives scientists precise genetic control over filamentous fungi, opening the door to novel bioactive compounds.
Researchers improve ADAR-based RNA editing precision using guide RNAs modeled on highly edited natural substrates.
China is increasing prestigious funding for early-career researchers. Will it reduce the intense competition stifling scientific innovation?
Scientists uncover how corals repeatedly evolved a specialized organelle to house algal partners — by hijacking their own lysosomal machinery.
A Lancet commentary exposes how future physicians are discouraged from voicing views on assisted dying — with real consequences for medicine.
A newly identified pressure-sensing channel in liver cells may hold the key to unlocking faster, more complete liver repair.
Science publishes an erratum correcting a 2026 research article on detecting supramolecular organic nanoparticles during heat wave events.
Researchers propose five criteria to identify the best immune aging biomarkers, with inflammaging scores and functional assays emerging as top candidates.