CAR-T and CAR-NK Cells Are Rewriting the Treatment Playbook for Deadly AML
A sweeping review of CAR-T and CAR-NK cell therapies in acute myeloid leukemia, covering clinical trial outcomes, key targets, and next-gen strategies.
675 articles in this topic
A sweeping review of CAR-T and CAR-NK cell therapies in acute myeloid leukemia, covering clinical trial outcomes, key targets, and next-gen strategies.
A completed exploratory trial evaluates whether a specialized compression garment can reduce discomfort and improve quality of life in pelvic lymphedema patients.
A randomized Phase 2 trial investigates whether PD-1 inhibitor discontinuation after early response is safe in non-small cell lung cancer.
A Cochrane meta-analysis of 17 RCTs finds blue light TURBT reduces bladder cancer recurrence and progression, especially in intermediate- and high-risk patients.
A phase 1 study finds paricalcitol combined with chemotherapy shows early promise against metastatic pancreatic cancer.
A 13-modality molecular analysis of 173 AML patients reveals distinct subtypes, metabolic reprogramming, and a machine-learning-validated therapy target.
A Dana-Farber/Broad Institute study links glioblastoma transcriptional states to survival outcomes in patients receiving immune checkpoint blockade.
A newly identified macrophage-Treg axis in tumor-draining lymph nodes may explain how colorectal cancer evades immune attack.
Cell publishes a tribute to Gregory J. Hannon, whose landmark work on RNAi and piRNA pathways reshaped cancer biology and gene regulation.
A newly discovered hepatic micropeptide suppresses liver cancer progression by jamming a key mitochondrial RNA processing complex.
New research reveals that whole-genome doubling triggers epigenetic changes that silence antigen presentation, letting tumors evade CD8+ T cells.
MIT researchers identify oncofetal cell states in colorectal tumors that mimic embryonic intestines and prime cancer cells for invasion.