Mesenchymal Drift Unifies the Hallmarks of Aging Into One Framework
Researchers propose that cells losing their identity and turning mesenchymal is the common thread linking all known hallmarks of aging.
4,153 articles in this topic
Researchers propose that cells losing their identity and turning mesenchymal is the common thread linking all known hallmarks of aging.
Beyond cholesterol: gene editing, siRNA, and immune reprogramming may soon reverse arterial plaque rather than just slow it.
New research links H. pylori infection to higher colorectal cancer risk, while gut-brain therapies show real promise for IBS sufferers.
A study of 90,000+ people finds every extra hour of uninterrupted sitting raises cancer mortality risk by 10%, but brief activity can reverse it.
A fractional laser shifted epigenetic markers at 83.9% of aging-linked DNA sites, with visible improvements lasting six months.
Sana Biotechnology's hypoimmune cell therapy may eliminate the need for lifelong immunosuppression in type 1 diabetes transplants.
Protagenic's PT00114 slashed stress-related cortisol markers and anxiety behaviors in rats, outperforming a standard CRF1 antagonist.
AlzeCure's NeuroRestore platform secures a landmark $2.2B licensing deal with QuantumCell, targeting Alzheimer's, Parkinson's, and depression.
A 52-week study shows patients with mild Alzheimer's can reliably complete unsupervised brain scans and cognitive tests at home.
A new in vivo therapy aims to reprogram macrophages inside the body using mRNA and lipid nanoparticles, potentially replacing complex cell transplants.
Over 3,000 carriers of the top Alzheimer's risk gene will track lifestyle and cognition for years in a landmark real-world study.
REP-0003 targets toxic intracellular cholesterol in artery walls — a rare disease breakthrough with wide cardiovascular aging implications.