Heart Disease

675 articles in this topic

Johns Hopkins Tests Deliberate Pacing Trick to Rescue Failing Hearts
Heart Health

Johns Hopkins Tests Deliberate Pacing Trick to Rescue Failing Hearts

A pilot trial explores whether intentionally inducing brief daily dyssynchrony via pacemaker can retrain failing heart muscle in humans.

Clinical Trial
Jun 14, 2026 0
High Salt Diet Triggers Aortic Dissection Through a Hidden Mitochondrial Pathway
Heart Health

High Salt Diet Triggers Aortic Dissection Through a Hidden Mitochondrial Pathway

Researchers discover that salt-triggered aortic dissection hinges on a receptor that guards mitochondrial energy metabolism in vessel walls.

Research Paper
Jun 14, 2026 0
FDA Approves Aficamten for Obstructive Hypertrophic Cardiomyopathy
Heart Health

FDA Approves Aficamten for Obstructive Hypertrophic Cardiomyopathy

Myqorzo (aficamten) wins FDA approval for symptomatic obstructive HCM, offering a novel cardiac myosin inhibitor option for patients.

Drug Approval
Jun 14, 2026 0
Phase 3 Trial Tests Tafamidis for TTR Amyloid Heart Disease
Heart Health

Phase 3 Trial Tests Tafamidis for TTR Amyloid Heart Disease

Pfizer's landmark trial examines whether tafamidis can safely treat transthyretin amyloid cardiomyopathy, a progressive and often fatal heart condition.

Clinical Trial
Jun 13, 2026 0
Telepharmacy Cuts Blood Pressure and Boosts Medication Adherence in Chronic Disease Patients
Heart Health

Telepharmacy Cuts Blood Pressure and Boosts Medication Adherence in Chronic Disease Patients

A Cochrane review of 21 RCTs finds remote pharmacist care may improve adherence and lower blood pressure in NCD patients.

Review
Jun 13, 2026 0
Common Food Additives Linked to Higher Hypertension and CVD Risk
Heart Health

Common Food Additives Linked to Higher Hypertension and CVD Risk

New JAMA research ties widely used food additives to elevated blood pressure and cardiovascular disease risk.

Research Paper
Jun 13, 2026 0
Monthly Shot vs Twice-Yearly Injection Battle for LDL Dominance in High-Risk Patients
Heart Health

Monthly Shot vs Twice-Yearly Injection Battle for LDL Dominance in High-Risk Patients

Phase 3 trial pits lerodalcibep against inclisiran to determine which PCSK9 inhibitor best cuts LDL in cardiovascular high-risk patients.

Clinical Trial
Jun 12, 2026 0
Resmetirom Targets LDL Cholesterol in Familial Hypercholesterolemia Trial
Heart Health

Resmetirom Targets LDL Cholesterol in Familial Hypercholesterolemia Trial

A Phase 2 trial tests once-daily oral resmetirom (MGL-3196) against placebo to reduce LDL-C in patients with inherited high cholesterol.

Clinical Trial
Jun 12, 2026 0
Phase 3 Trial Tests Obicetrapib for Hard-to-Treat High Cholesterol
Heart Health

Phase 3 Trial Tests Obicetrapib for Hard-to-Treat High Cholesterol

A completed Phase 3 trial evaluates obicetrapib added to maximum lipid-lowering therapy in patients with familial hypercholesterolemia and ASCVD.

Clinical Trial
Jun 12, 2026 0
9-Apolipoprotein Blood Panel Outperforms Standard Cholesterol Tests for Heart Attack Risk
Heart Health

9-Apolipoprotein Blood Panel Outperforms Standard Cholesterol Tests for Heart Attack Risk

A mass spectrometry apolipoprotein panel predicts cardiovascular events and identifies who gains the most from PCSK9 inhibitor therapy.

Research Paper
Jun 12, 2026 0
Hidden Heart Risk: Remnant Cholesterol Raises ASCVD Risk More Than LDL But Gets Undertreated
Heart Health

Hidden Heart Risk: Remnant Cholesterol Raises ASCVD Risk More Than LDL But Gets Undertreated

A 94,000-person study finds high remnant cholesterol raises heart disease risk 45% — yet triggers far less statin prescribing than high LDL.

Research Paper
Jun 12, 2026 0
Heart Protein RND3 Shields Against Heart Attack Damage by Fixing Fuel Metabolism
Heart Health

Heart Protein RND3 Shields Against Heart Attack Damage by Fixing Fuel Metabolism

A newly discovered mitochondrial protein boosts cardiac glucose burning and dramatically reduces heart injury after ischemia-reperfusion.

Research Paper
Jun 12, 2026 0
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