Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,795 articles
A comprehensive review maps cardiovascular, metabolic, hormonal, and neuromodulatory biomarkers that decode how endurance exercise reshapes the body.
A wave of cardiology findings reshapes heart failure diagnosis, reveals stroke drug promise, and links social ties to longevity.
Researchers from Northeastern and Harvard mapped 6,442 drugs against aging hallmark genes using protein interaction networks to identify longevity candidates.
Graph neural networks pinpoint synergistic natural compound pairs targeting four core aging pathways simultaneously.
The Dog Aging Project enrolled 976 companion dogs to collect longitudinal multi-omic data—epigenome, microbiome, metabolome—as a translational aging model.
Scientists mapped 160 canine diseases across 26,614 dogs, uncovering how conditions cluster together—and how these patterns intensify with age.
A 900-dog study maps how gut microbiome composition shifts with age, diet, and behavior — with striking parallels to human aging patterns.
A landmark Dog Aging Project study finds plasma metabolites predicting all-cause mortality in dogs mirror those in nine human cohort studies.
A comprehensive review reveals the mechanisms behind thymic decline with age and evaluates emerging strategies to restore T cell production and immune function.
Go beneath the surface of mitochondrial bioenergetics to understand exactly how CoQ10 shuttles electrons, builds the proton gradient, and why its redox cycling is central to both energy production and aging.
Scientists identify a primate-specific long non-coding RNA that accelerates cellular aging, opening new targets for senescence intervention.
Generation Lab's updated test measures 460+ biomarkers with separate male and female analyses, tracking organ aging and treatment response.
