3258 articles in this topic
Tiny lab-engineered peptides mimicking the brain's own antioxidant enzyme show protective effects across a striking range of age-related diseases.
New research shows mitochondrial H₂O₂ isn't just a toxic byproduct—it actively orchestrates neural stem cell proliferation and cortical layering.
A new study shows ferroptosis drives cellular senescence, and blocking it with ferrostatin-1 extends lifespan and healthspan in worms and aging mice.
GH drops sharply as we age, mimicking deficiency states — yet boosting it in older adults shows mixed results and real risks.
A supervised resistance exercise program improved physical performance and reduced frailty biomarkers in adults aged 100+, a first-of-its-kind trial.
A longitudinal study of 54 adults finds COVID-19 infection significantly accelerates biological aging across multiple epigenetic clocks.
A randomised trial finds monthly 5-day fasting-mimicking diet cycles significantly reduce myocardial triglyceride content in type 2 diabetes patients.
A 2025 review finds that metabolic gains from TRE and intermittent fasting are largely driven by caloric reduction, not meal timing alone.
A 6-month fasting-mimicking diet restored fat-burning flexibility and improved albuminuria in T2D patients, with metabolomics revealing who responds best.
New review synthesizes preclinical and clinical evidence showing fasting may sensitize tumors to chemotherapy while protecting healthy cells.
A new mouse study shows fisetin senolytic treatment reverses age-related endothelial dysfunction by eliminating senescent cells and reducing the SASP factor CXCL12.
Fisetin encapsulated in liposomes significantly reduces IL-6 and IL-8 secretion in senescent lung cells, revealing potent senomorphic but not senolytic activity.
