Antidepressants Sertraline and Indatraline Trigger Cancer Cell Death via Cholesterol
Two common antidepressants cause cholesterol buildup in cancer cell lysosomes, triggering immunogenic cell death that helps immune system fight tumors.
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Two common antidepressants cause cholesterol buildup in cancer cell lysosomes, triggering immunogenic cell death that helps immune system fight tumors.
Major review reveals functional biomarkers outperform molecular aging clocks for predicting mortality and disease risk.
Revolutionary dental therapy uses stem cells to regenerate living tooth pulp, potentially replacing root canals with natural healing.
New research reveals how naked mole-rats activate a unique DNA repair mechanism that may explain their extraordinary longevity.
Comprehensive review reveals how telomerase biogenesis regulates telomere maintenance, offering new therapeutic targets for aging disorders.
Comprehensive review reveals promising new drug targets and immunotherapy approaches for myelofibrosis beyond current JAK inhibitor limitations.
New review reveals how damaged mitochondria accelerate aging through metabolic reprogramming, inflammation, and cellular dysfunction.
New structural insights show how telomerase enzymes pair up through H/ACA RNA complexes, advancing our understanding of cellular aging mechanisms.
Comprehensive review reveals glioblastoma's devastating prognosis with only 5.5% five-year survival rate and key genetic markers for treatment.
Comprehensive review reveals how parabiosis, organoids, and assembloids complement each other to model complex diseases from systemic to tissue levels.
Breakthrough skin organoids contain blood vessels, hair follicles, and immune cells, opening new paths for disease modeling and regenerative medicine.
Researchers outline vision for fully automated bioprinting laboratories that use AI and robotics to manufacture tissues and organs with minimal human intervention.