Longevity & Aging
Growth Hormone Declines With Age But Replacing It May Not Extend Life
GH drops sharply as we age, mimicking deficiency states — yet boosting it in older adults shows mixed results and real risks.
Research Paper
May 18, 2026 0
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Longevity & Aging
12-Week Resistance Training Reverses Frailty and Boosts Function in Centenarians
A supervised resistance exercise program improved physical performance and reduced frailty biomarkers in adults aged 100+, a first-of-its-kind trial.
Research Paper
May 18, 2026 0
Longevity & Aging
COVID-19 Measurably Accelerates Epigenetic Aging Over Three Years
A longitudinal study of 54 adults finds COVID-19 infection significantly accelerates biological aging across multiple epigenetic clocks.
Research Paper
May 18, 2026 0
Longevity & Aging
Fasting-Mimicking Diet Cuts Heart Fat in Type 2 Diabetes Over 12 Months
A randomised trial finds monthly 5-day fasting-mimicking diet cycles significantly reduce myocardial triglyceride content in type 2 diabetes patients.
Research Paper
May 18, 2026 0
Longevity & Aging
Time-Restricted Eating Benefits May Be Mostly About Eating Less, Not Eating Earlier
A 2025 review finds that metabolic gains from TRE and intermittent fasting are largely driven by caloric reduction, not meal timing alone.
Research Paper
May 18, 2026 0
Longevity & Aging
Periodic Fasting Restores Metabolic Flexibility and Reduces Kidney Damage in Type 2 Diabetes
A 6-month fasting-mimicking diet restored fat-burning flexibility and improved albuminuria in T2D patients, with metabolomics revealing who responds best.
Research Paper
May 18, 2026 0
Longevity & Aging
Fasting and Fasting-Mimicking Diets Show Promise as Cancer Therapy Boosters
New review synthesizes preclinical and clinical evidence showing fasting may sensitize tumors to chemotherapy while protecting healthy cells.
Research Paper
May 18, 2026 0
Longevity & Aging
Fisetin Clears Senescent Cells and Restores Blood Vessel Function via CXCL12
A new mouse study shows fisetin senolytic treatment reverses age-related endothelial dysfunction by eliminating senescent cells and reducing the SASP factor CXCL12.
Research Paper
May 18, 2026 0
Longevity & Aging
Liposomal Fisetin Suppresses Inflammatory SASP Without Killing Senescent Cells
Fisetin encapsulated in liposomes significantly reduces IL-6 and IL-8 secretion in senescent lung cells, revealing potent senomorphic but not senolytic activity.
Research Paper
May 18, 2026 0
Longevity & Aging
Kaempferol Triggers Hormetic Responses That May Slow Aging Across Multiple Systems
A new review finds kaempferol, a common dietary flavonoid, acts as a senolytic agent and produces dose-dependent hormetic effects tied to aging biology.
Research Paper
May 18, 2026 0
Longevity & Aging
Methylene Blue Cuts Postoperative Delirium by Calming Brain Inflammation
FDA-approved methylene blue reduced delirium-like behavior in surgical mice by suppressing neuroinflammation and repairing the blood-brain barrier.
Research Paper
May 18, 2026 0
Longevity & Aging
Methylene Blue Reverses Fatal Brain Malaria and Reveals Nine Blood Biomarkers
A primate study shows methylene blue treats fatal cerebral malaria and uncovers neutrophil-linked genes as diagnostic biomarkers.
Research Paper
May 18, 2026 0