Alzheimer's

746 articles in this topic

Blocking TRPV4 Channel Restores Brain Fluid Clearance After Stroke
Brain Health

Blocking TRPV4 Channel Restores Brain Fluid Clearance After Stroke

Inhibiting TRPV4 channels in mice restored glymphatic drainage, cut cerebral edema, and improved neurological recovery after ischemic stroke.

Research Paper
May 13, 2026 0
BACE Inhibitor Atabecestat Trial in Pre-Symptomatic Alzheimer's Risk Terminated Early
Brain Health

BACE Inhibitor Atabecestat Trial in Pre-Symptomatic Alzheimer's Risk Terminated Early

A phase 2/3 trial of the BACE inhibitor atabecestat in amyloid-positive asymptomatic adults was terminated before completion, raising questions about this drug class.

Clinical Trial
May 13, 2026 0
Canada's Brain Health PRO Trial Tests Online Dementia Prevention at Scale
Brain Health

Canada's Brain Health PRO Trial Tests Online Dementia Prevention at Scale

A completed Canadian platform trial enrolls 354 at-risk adults in a multidomain online brain health program targeting dementia prevention.

Clinical Trial
May 13, 2026 0
Current Drugs for Friedreich Ataxia Show Little Benefit After One Year
Brain Health

Current Drugs for Friedreich Ataxia Show Little Benefit After One Year

A Cochrane meta-analysis of 8 RCTs finds most pharmacological treatments fail to improve ataxia scores, though upper limb dexterity may benefit.

Review
May 13, 2026 0
Diabetes Treatment May Mask Alzheimer's Biomarker Signals in Research
Brain Health

Diabetes Treatment May Mask Alzheimer's Biomarker Signals in Research

A new study warns that diabetes medications could confound Alzheimer's biomarker studies, distorting our understanding of the diabetes-dementia link.

Research Paper
May 13, 2026 0
Correction Issued for Study on Mental Health of Early-Career Dementia Researchers
Brain Health

Correction Issued for Study on Mental Health of Early-Career Dementia Researchers

A formal erratum updates a 2026 cross-sectional survey on mental health factors affecting early-career dementia researchers worldwide.

Research Paper
May 13, 2026 0
Faulty Ion Channel in Serotonin Neurons May Drive Early Alzheimer's Spread
Brain Health

Faulty Ion Channel in Serotonin Neurons May Drive Early Alzheimer's Spread

A key potassium channel, KCNA4, is lost in vulnerable brainstem neurons at Braak II โ€” potentially fueling tau pathology progression.

Research Paper
May 13, 2026 0
Brain-Controlled Hearing System Lets You Focus on One Voice in a Crowd
Brain Health

Brain-Controlled Hearing System Lets You Focus on One Voice in a Crowd

A real-time brain-computer interface decodes auditory attention and amplifies the speaker you choose, beating today's hearing aids.

Research Paper
May 13, 2026 0
Hippocampal CA1 Region Drives Why Some Mice Learn Generosity and Others Don't
Brain Health

Hippocampal CA1 Region Drives Why Some Mice Learn Generosity and Others Don't

New research pinpoints the hippocampal dorsal CA1 as the neural hub encoding individual differences in prosocial vs. selfish behavior.

Research Paper
May 13, 2026 0
New Brain Mapping Tool Reveals Lymphocytes Drive Inflammation in Brain Aging
Brain Health

New Brain Mapping Tool Reveals Lymphocytes Drive Inflammation in Brain Aging

IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.

Research Paper
May 13, 2026 0
Harvard Researchers Warn AI Health Tools Are Leaving Vulnerable Patients Behind
Brain Health

Harvard Researchers Warn AI Health Tools Are Leaving Vulnerable Patients Behind

A New England Journal of Medicine perspective argues that healthcare AI risks deepening inequities for underserved populations.

Research Paper
May 13, 2026 0
A Physician Reflects on What Routine Medicine Reveals About Human Connection
Brain Health

A Physician Reflects on What Routine Medicine Reveals About Human Connection

A NEJM perspective piece explores the hidden meaning and emotional depth found in everyday clinical encounters.

Research Paper
May 13, 2026 0
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