7263 articles
MAIT cells appear to provide protective immune surveillance in Lynch syndrome carriers who haven't developed colorectal cancer, suggesting new risk stratification tools.
A receptor that keeps firing inside pain cells may explain why IBS discomfort is so persistent and hard to treat.
Newly characterized lipid mediators derived from DHA may defend against Alzheimer's, Parkinson's, stroke, and macular degeneration.
A comprehensive review reveals how transsulfuration pathway products and H₂S-donors may offer new therapeutic avenues for hyperhomocysteinemia.
NAC-coated molybdenum disulfide quantum dots target kidney mitochondria, simultaneously neutralizing ROS and restoring depleted antioxidant enzymes in AKI models.
The TCA cycle is a central metabolic hub linking energy production, amino acid synthesis, and cholesterol regulation — all critical to aging biology.
A phase 2 trial finds tesamorelin reduces abdominal obesity in virally suppressed HIV patients but shows no significant cognitive improvement.
A case report reveals MK-677, a widely used growth hormone secretagogue, triggered significant liver damage in a healthy man in his 30s.
Scientists created stem cell models of Wiedemann-Rautenstrauch syndrome, uncovering how POLR3A mutations disrupt nucleoli and trap telomerase RNA.
A comprehensive 2025 review charts the signaling pathways, drug targets, and emerging strategies scientists are using to slow human aging.
A systematic review reveals how bioactive food compounds modulate telomerase activity to potentially prevent hepatocellular carcinoma.
A 2025 review maps the most promising drug targets and novel strategies—from gene therapy to gut microbiome interventions—for treating MASH.
